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Franciscan Missionaries of Our Lady Health System

Questions or Suggestions Drug Information Questions

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*COVID-19 Pharmacy Resources

Franciscan Missionaries of Our Lady Health System

Questions or Suggestions Drug Information Questions

Black Box Warning

Please review each of these drugs carefully.

abacavir	Hypersensitivity
abacavir-lamivudine	Abacavir: hypersensitivity reactions; lactic acidosis, hepatomegaly
abacavir/dolutegravir/lamivudine	Hypersensitivity Reactions, Lactic Acidosis and Severe Hepatomegaly; Exacerbations of Hepatitis B
abacavir/lamivudine/zidovudine	Hypersensitivity Reactions, Lactic Acidosis and Severe Hepatomegaly; Exacerbations of Hepatitis B
abobotulinumtoxinA	Distant spread of toxin effect
acetaminophen	Hepatotoxicity
acetaminophen-codeine	Addiction, Abuse, And Misuse; Life-Threatening Respiratory Depression; Risks From Concomitant Use With Benzodiazepines
acetaminophen-hydrocodone	Acetaminophen - Hepatotoxicity Hydrocodone - Risks from Concomitant Use with Benzodiazepines or Other CNS Depressants
acetaminophen-oxycodone	Addiction, Abuse, and Misuse; Life-Threatening Depression; Accidental Exposure; Neonatal Opioid Withdrawal Syndrome; and Hepatotoxicity
acetaminophen-tramadol	Addiction, Abuse, and Misuse; Life-Threatening Depression; Accidental Exposure; Neonatal Opioid Withdrawal Syndrome; and Hepatotoxicity
acetylcysteine	Inhalation solution: not for injection
acitretin	Pregnancy/Teratogenecity
adalimumab	Infection risk; malignancy in children and adolescents
ado-trastuzumab emtansine	Hepatotoxicity, Cardiac Toxicity, Embryo-Fetal Toxicity
alemtuzumab	Autoimmunity, Infusion Reactions, and Malignacies; Autoimmune Hepatitis - LEMTRADA; Cytopenias, Infusion-Related Reactions, and Infections - CAMPATH
alglucosidase alfa	Anaphylaxis; Cardiorespiratory Failure
aliskiren	Pregnancy risk
ALPRAZolam	Risks From Concomitant Use in Opioids
alprostadil	Apnea
alvimopan	Short-term hospital use only
amikacin	Neurotoxicity; nephrotoxicity
aMILoride	Hyperkalemia
amiodarone	Oral: Pneumonitis; Proarrhythmic Effects
amitriptyline	Suicidal ideation in children, adolescents
amitriptyline-perphenazine	Increased Mortality in Elderly Patients with Dementia-Related Psychosis
amoxapine	Suicidal Ideation
amphetamine-dextroamphetamine	Abuse/diversion potential; drug dependence
amphotericin B	Noninvasive fungal disease; avoid overdose
apixaban	Discontinuation without anticoagulation
arformoterol	Asthma Related Death
ARIPiprazole	Elderly patients with dementia related psychosis
arsenic trioxide	Cardiac toxicity
ascorbic acid-carbonyl iron	Iron Overdose Risk
ascorbic acid-iron polysaccharide	Iron Overdose Risk
asenapine	Mortality in elderly patients with dementia related psychosis
asparaginase Erwinia chrysanthemi	Note: Latest labeling (3/2007) does not include prior boxed warning.
atenolol	Avoid abrupt withdrawal
atomoxetine	Suicidal Ideation
avalglucosidase alfa	Severe Hypersensitivity Reactions, Infusion-Associated Reactions, and Risk of Acute Cardiorespiratory Failure in Susceptable Patients
azaTHIOprine	Risk of neoplasia, infections
azilsartan (non-formulary)	Pregnancy risk
bacitracin	Injection: Nephrotoxicity
baclofen	Intrathecal: Abrupt discontinuation
balsalazide	Renal Impairment - Giazo
baricitinib (non-formulary)	Serious Infections, Malignancy, and Thrombosis
BCG	Risk of infection; biohazard handling precautions
belantamab mafodotin	Ocular Toxicity
belatacept	Post transplant lymphoproliferative disorder; serious infections
benzathine penicillin-procaine penicillin	Not for Intravenous Use
bevacizumab	GI perforation; wound healing complications
bictegravir/emtricitabine/tenofovir	Post Treatment Acute Exacerbation of Hepatitis B
bleomycin	Pulmonary Fibrosis; Idiosyncratic Reactions
blinatumomab	Cytokine Release Syndrome and Neurological Toxicities
bosentan	Risks of Hepatotoxicity and Embryo-Fetal Toxicity
brentuximab vedotin	Progressive Multifocal Leukoencephalopathy (PML)
budesonide-formoterol	Asthma Related Death
bumetanide	Potent diuretic
bupivacaine	Intravascular injection risk; 0.75% strength caution; Risk of Use in Obstetrical Anesthesia
bupivacaine-epinephrine	Bupivacaine: Intravascular injection risk; 0.75% strength caution; Risk of Use in Obstetrical Anesthesia
bupivacaine-meloxicam	Risk of Serious Cardiovascular and Gastroinstestinal Events
buprenorphine	Addiction, Abuse, And Misuse; Respiratory Depression; Neonatal Opioid Withdrawal Syndrome; Risks From Concomitant Use With Benzodiazepines
buprenorphine-naloxone (non-formulary)	Implant: Implant Migration, Protrusion, Expulsion, and Nerve Damage Associated with Insertin and Removal
buPROPion	Suicidal Ideation
butorphanol	Addiction, Abuse, And Misuse; Respiratory Depression; Neonatal Opioid Withdrawal Syndrome; and Risks From Concomitant Use With Benzodiazepines
cabazitaxel	Hemtalogical & Hypersensitivity Reactions
candesartan (non-formulary)	Pregnancy risk
capecitabine	Warfarin Interaction
captopril (non-formulary)	Pregnancy risk
captopril-hydrochlorothiazide (non-formulary)	Captopril: Pregnancy risk
carBAMazepine	Hematological Risk; Serious Dermatologic Reactions
carbidopa	Bolded (not boxed): Carbidopa dosing
carbidopa-levodopa	Bolded (not boxed): Carbidopa dosing
carbidopa/entacapone/levodopa	Bolded (not boxed): Carbidopa dosing
CARBOplatin	Myelosuppression; Anaphylaxis risk
carfilzomib	Cardiac Toxicities; Tumor Lysis Syndrome; Pumonary Toxicity; Dyspnea; Hyprertension
cariprazine (non-formulary)	Increased Mortality in Elderly Patients with Dementia-Related Psychosis
carmustine	Bone Marrow Suppression; Pulmonary Toxicity
celecoxib	Cardiovascular, gastrointestinal risk
certolizumab	Risk of Serious Infections and Malignancy
cetuximab	Infusion Reactions; Cardiopulmonary Arrest
chlorambucil	Bone marrow suppression; teratogen
chlordiazePOXIDE	Risks From Concomitant Use With Opioids
chlordiazepoxide-clidinium	Risks From Concomitant Use With Opioids
chlorpheniramine-hydrocodone	Tussionex Pennkinetic and Vituz - Risks from Concomitant Use with Benzodiazepines or Other CNS Depressants
chlorproMAZINE	Mortality in elderly with dementia
cidofovir	Nephrotoxicity; neutropenia
cilostazol	CHF patient contraindication
ciprofloxacin	Tendinitis; tendon rupture
CISplatin	Nephrotoxicity; Myelosuppression
citalopram	Suicidal Thoughts and Behaviors
cladribine	Bone Marrow Suppression; Neurotoxicity; Nephrotoxicity
clindamycin	Pseudomembranous colitis
cloBAZam	Risk From Concomitant Use with Opiods
clomiPRAMINE	Suicidal Ideation
clonazePAM	Risk From Concomitant Use With Opioids
cloNIDine	Epidural Clonidine
clopidogrel	Poor CYP2C19 metabolizers
clorazepate	Risks From Concomitant Use With Opioids
cloZAPine	Agranulocytosis, myocarditis, seizure risk
coagulation factor VIIa	Serious Thrombotic Adverse Events Associated with Recombinant Coagulation Factor VIIa Outside Label Indicatons
coagulation factor Xa	Thromboembolic Risks, Ischemic Risks, Cardiac Arrest, and Sudden Deaths
cobicistat/darunavir/emtricitabine/tenof	Post Treatment Acture Exacerbation of Hepatitis B
cobicistat/elvitegravir/emtricitabine/tenofov	Lactic acidosis, severe hepatomegaly; hepB co-infection
cocaine topical	Topical: Not for injection or ophthalmic use.
codeine	Addiction, Abuse, And Misuse; Respiratory Depression; Neonatal Opioid Withdrawal Syndrome; and Risks From Concomitant Use With Benzodiazepines
codeine-guaifenesin	Codeine in children: death due to ultra-rapid metabolism
codeine-promethazine	Codeine in children: death due to ultra-rapid metabolism Promethazine: contraindicated in patients < 2 years
codeine/guaifenesin/pseudoephedrine	Codeine in children: death due to ultra-rapid metabolism
codeine/phenylephrine/promethazine	Codeine in children: death due to ultra-rapid metabolism Promethazine: contraindicated in patients < 2 years
conjugated estrogens	Endometrial cancer; cardiovascular; dementia risk
conjugated estrogens topical	Endometrial cancer; cardiovascular; dementia risk
cycloSPORINE	Infection, neoplasm, nephrotoxicity risk
cytarabine	Prior to initiation of therapy
cytarabine liposomal-daunorubicin liposomal	Do Not Interchange with other Daunorubicin and/or Cytarabine Containing Products
dabigatran	Discontinuation without anticoagulation
dacarbazine	Hemopoietic depression; hepatic necrosis risk
DACTINomycin	Handling precautions; extravasation risk
dalfopristin-quinupristin	Approved indication (Warning Removed)
danazol	Pregnancy contraindication; stroke risk; hepatic risk with long term use; benign intracranial hypertension
dantrolene	Hepatotoxicity
darbepoetin alfa	Mortality, serious CV events, tumor progression or recurrence
DAUNOrubicin	Cardiac, myelosuppression, extravasation risk
denosumab	Prolia - Severe Hypocalcemia in Patients with Advanced Kidney Disease
desipramine	Suicidal Ideation
desmopressin	Hyponatremia Hyponatremia (Nasal Spray)
desvenlafaxine	Suicidal ideation
dexmethylphenidate	Caution in drug dependent patients; supervised withdrawal
dextromethorphan-promethazine	Promethazine: Contraindicated in patients < 2 years
dextromethorphan-quinidine	Quinidine: Active antiarrhythmic therapy may increase mortality
diatrizoate	Not for intrathecal use
diazePAM	Risks From Concomitant Use With Opioids
diclofenac	Cardiovascular, gastrointestinal risk
diclofenac topical	Cardiovascular, gastrointestinal risk
diclofenac-misoprostol	Risk of Uterine Rupture, Abortion, Premature Birth, Birth Defects; and Serious Cardiovascular and Gastrointestinal Events
dihydroergotamine	Drug interaction risk
dinoprostone topical	Suppository: use recommended dose
disopyramide	Mortality Risk
disulfiram	Administer with patient consent
divalproex sodium	Hepatotoxicity; mitochondrial disease; fetal risk
DOCEtaxel	Hepatic dysfunction, hypersensitivity risk
dofetilide	Initiation or re-initiation monitoring
dolutegravir-lamivudine	Patients Co-Infected with Hepatitis B Virus (HBV) & Human Immunodeficiency Virus (HIV-1)
DOPamine	Peripheral ischemia risk
doravirine/lamivudine/tenofovir	Post-Treatment Acute Exacerbation of Hepatitis B
doxepin	Suicidal Ideation
DOXOrubicin	Cardiac, hepatic, myelosuppression, extravasation risk
DOXOrubicin liposomal	Cardiac, acute infusion reaction, myelosuppresssion risk
dronedarone	Contraindication in certain CHF conditions
droperidol	QT prolongation; cardiac risk
droxidopa	Supine Hypertension
DULoxetine	Suicidal Ideation
ecallantide	Anaphylaxis
eculizumab	Meningococcal Infection
efavirenz/emtricitabine/tenofovir	Lactic Acidosis; Severe Hepatomegaly with Steatosis and Post Treatment Exacerbation of Hepatitis B
elbasvir-grazoprevir	Risk of Hepatitis B Virus Reactivation in Patients Coninfected with HCV and HBV
elranatamab	Cytokine Release Syndrome and Neurologic Toxicity, including Immune Effector Cell-Associated Neurotoxicity Syndrome
emicizumab	Thrombotic Microangiopathy and Thromboembolism
emtricitabine	Lactic Acidosis, Severe Hepatomegaly
emtricitabine-tenofovir	Lactic acidosis; severe hepatomegaly; hepB co-infection
emtricitabine/rilpivirine/tenofovir	Lactic acidosis, severe hepatomegaly; hepB co-infection
enalapril	Pregnancy risk
enfortumab vedotin	Serious Skin Reactions
enoxaparin	Spinal/epidural hematoma risk
epcoritamab	Cytokine release syndrome (CRS) and Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS)
epiRUBicin	Cardiac Toxicity, Secondary Malignancies, Extravasation & Tissue Necrosis, and Severe Myelosuppression
epoetin alfa	Risk of mortality, tumor progression, cardiac events
eprosartan (non-formulary)	Pregnancy risk
escitalopram	Suicidal ideation
estazolam (non-formulary)	Risks From Concomitant Use With Opioids
esterified estrogens	Endometrial cancer; cardiovascular; dementia risk
esterified estrogens-methyltestosterone	Endometrial cancer; cardiovascular; dementia risk
estradiol	Transdermal: endometrial cancer; cardiovascular; dementia risk Vaginal cream/tab: endometrial cancer; cardiovascular; dementia risk Oral: ndometrial cancer; cardiovascular; dementia risk
estradiol topical	Endometrial cancer; cardiovascular; dementia risk
eszopiclone (non-formulary)	Risk of Serious Injuries With Certain Prescription Insomnia Medications
etanercept	Infection Risk; Tuberculosis; Malignancy in Children and Adolescents
ethacrynic acid	Potent Diuretic
ethinyl estradiol-norethindrone	Cigarette smoking; risk of cardiovascular disease
etodolac	Cardiovascular; gastrointestinal risk
etoposide	Myelosuppression risk
etoposide phosphate	Myelosuppression risk
exenatide	Extended Release Injection: Risk of thyroid c-cell tumors
fam-trastuzumab deruxtecan	Interstitial Lung Disease and Embryo-Fetal Toxocity
fat emulsion, intravenous	Cautious use in infants Death in preterm infants
febuxostat	Cardiovascular Death
felbamate	Aplastic anemia; liver failure risk
fentaNYL	Buccal Table & Injection: Serious adverse events, deaths; abuse potential Nasal Spray: Schedule II Controlled Substance: Abuse potential Sublingual Spray: Risk of respiratory depression, medication errors, abuse potential Transdermal: High concentration of Schedule II opioid agonist
ferrous gluconate	Iron Overdose Risk
ferrous sulfate	Iron Overdose Risk
ferumoxytol	Risk For Serious Hypersensitivity/Anaphylaxis Reactions
flecainide	Cardiovascular risk
flucytosine	Hepatic, hematologic risks; caution in renal impairment
fludarabine	Neurotoxicity, hemolytic anemia risk
flumazenil	Seizure Risk
fluorouracil	Hematologic risk
FLUoxetine	Suicidal Ideation
fluPHENAZine	Mortality in elderly with dementia
flurazepam (non-formulary)	Risks From Concomitant Use With Opioids
flutamide	Hepatotoxicity
fluticasone-salmeterol	Salmeterol: asthma related death; pediatric and adolescent patients
fluticasone-vilanterol	Vilanterol: Asthma-related death
fluvoxaMINE	Suicidal Ideation
fondaparinux	Spinal/epidural hematoma risk
formoterol fumarate (non-formulary)	Asthma Related Death
formoterol-mometasone (non-formulary)	Asthma Related Death
foscarnet	Nephrotoxicity; seizure risk
fosphenytoin	Cardiovascular risk with rapid infusion
furosemide	Potent Diuretic
gadobenate dimeglumine	Nephrogenic Systemic Fibrosis
gadobutrol	Nephrogenic Systemic Fibrosis
gadodiamide	Nephrogenic Systemic Fibrosis
gadoterate meglumine	Nephrogenic Systemic Fibrosis
gadoteridol	Nephrogenic Systemic Fibrosis
gadoxetate	Nephrogenic Systemic Fibrosis
ganciclovir	Hematological toxicity; IV and oral different indications
gemtuzumab ozogamicin	Hepatotoxicity
gentamicin	Ototoxicity; Nephrotoxocity
glecaprevir-pibrentasvir	Risk of Hepatitis B Virus Reactivation in Patients Coninfectd with HCV and HBV
golimumab	Risk of Serious Infections, Malignancy in Children and Adolescents
haloperidol	Mortality in elderly with dementia
heparin	Spinal/Epidural Hematomas
hetastarch	Renal injury risk
homatropine-hydrocodone	Hycodan - Risks from Concomitant Use with Benzodiazepines or Other CNS Depressants
hyaluronidase-immune globulin	Renal dysfunction, acute renal failure
hyaluronidase-rituximab	Fatal Infusion Reaction; Mucocutaneous Reactions; Progressive Multifocal Leukoencephalopathy; Hep b Reactivation
hyaluronidase-trastuzumab	Cardiomyopathy, Embryo-Fetal Toxicity and Pulmonary Toxicity
hyaluronidase/pertuzumab/trastuzumab	Cardiomyopathy, Embryo-Fetal Toxicity, and Pulmonary Toxicity
hydrochlorothiazide-triamterene	Hyperkalemia
hydrocodone-ibuprofen	NSAIDS - Cardiovascular; gastrointestinal risk Hydrocodone - Addiction, Abuse, and Misuse
HYDROmorphone	Injection: Respiratory depression risk; abuse potential Injection, High Potency: Opioid-tolerant patients only; Respiratory depression risk; abuse potential Oral, extended release: Opioid-tolerant patients only; overdose risk; abuse potential Oral, liquid & tablets: Abuse potential; respiratory depression; neonatal withdrawal; alcohol interaction
hydroxychloroquine	Prior to initiation of therapy
hydroxyurea	Prior to initiation of therapy
ibuprofen	Cardiovascular; gastrointestinal risk
ibutilide	Potentially Fatal Arrhythmias
IDArubicin	Cardiotoxicity; myelosuppression; renal/hepatic impairment; avoid extravasation
ifosfamide	Urotoxicity; myelosuppressionm CNS toxicity
imipramine	Suicidal ideation
immune globulin intramuscular	Renal dysfunction, acute renal failure
immune globulin intravenous	Renal dysfunction, acute renal failure
immune globulin intravenous and subcutaneous	Renal dysfunction, acute renal failure
incobotulinumtoxinA	Distant Spread of Toxin Effect
indacaterol (non-formulary)	Asthma Related Death
indomethacin	Cardiovascular; gastrointestinal risk
inFLIXimab	Serious infection risk; hepatosplenic t-cell lymphomas; malignancy
inotuzumab ozogamicin	Hepatotoxicity, Including Hepatic Veno-Occlusive Disease (VOD - also known as Sinusoidal Obstruction Syndrome) and Increased Risk of Post-Hematopoietic Stem Cell Transplant (HSCT) Non-Relapse Mortality
iodixanol	Not for intrathecal use
iopamidol	Not for intrathecal use
ioversol	Not for Intrathecal
ipilimumab	Immune-Mediated Adverse Reactions
irbesartan (non-formulary)	ACE inhibitor pregnancy risk
irinotecan	Severe diarrhea
irinotecan liposomal	Severe diarrhea
iron dextran	Injection: Anaphylactic reaction risk
iron sucrose	Iron overdose risk
isoniazid	Hepatitis
itraconazole	Congestive heart failure, drug interactions
ixabepilone	Toxicity in hepatic impariment
ketamine	Emergence reactions; psychological manifestations
ketoconazole	Oral: hepatoxicity, drug interactions
ketorolac	Duration of therapy; max dose; GI, cardiovascular, bleeding, renal risk Nasal Spray - Risk of Serious Cardiovascular and Gastrointestinal Events
lamiVUDine	Lactic acidosis, hepatomegaly; exacerbations of hepatitis b; dosing formulation
lamivudine-zidovudine	Lamivudine: Lactic acidosis, hepatomegaly; exacerbations of hepatitis b; dosing formulation Zidovudine: Hematological adverse events; myopathy; lactic acidosis; hepatomegaly
lamoTRIgine	Serious dermatological reactions
lecanemab	Amyloid Related Imaging Abnormalities
leflunomide	Pregnancy risk
levoFLOXacin	Tendinitis, tendon rupture; Pediatric Use
levonorgestrel	Bolded (not boxed): Not Protective Against HIV
levothyroxine	Treatment of obesity or weight loss
lidocaine topical	Lidocaine, viscous: Do NOT use for teething pain
linaclotide	Risk of Serious Dehydration in Pediatric Patients
lincomycin	Clostridium difficile associated diarrhea
lindane topical	Neurotoxicity
liothyronine	Treatment of obesity or weight loss
liraglutide	Risk of Thyroid C-cell Tumors
lisdexamfetamine	High abuse/diversion potential; drug dependence
lisinopril	ACE inhibitor pregnancy risk
lithium	Monitoring recommendations
lomustine	Bone marrow suppression
lopinavir-ritonavir	Ritonavir: Drug interactions
LORazepam	Risks From Concomitant Use With Opioids
losartan	Pregnancy risk
loxapine	Elderly patients with dementia related psychosis Aerosol: Bronchospasm
lurasidone	Mortality in elderly patients with dementia related psychosis
LVP solution	Extraneal: Unrecognized Hypoglycemia Resulting From Drug-Device Interaction
lymphocyte immune globulin, anti-thy (equine)	Prior to initiation of therapy
mannitol	Severe bronchospasm risk
maraviroc	Hepatotoxicity
margetuximab	Left Ventricular Dysfunction and Embryo-Fetal Toxicity
medroxyPROGESTERone	Oral: Cardiovascular and other risks Injection: Loss of Bone Mineral Density
meloxicam	Cardiovascular; gastrointestinal risk
meperidine	Addiction, Abuse, and Misuse; Life-Threatening Respiratory Depression; Accidental Exposure; Neonatal Opioid Withdrawal Syndrome
mercaptopurine	Bolded (not boxed): initiation of therapy
mestranol-norethindrone	Cigarette smoking; risk of cardiovascular disease
metFORMIN	Lactic Acidosis
methacholine	Diagnostic Use Only; Severe Bronchoconstriction
methadone	Risk during initiation of or conversion to methadone
methohexital	Continuous monitoring of respiratory and cardiac function
methotrexate	Bone marrow, liver, lung and kidney toxicity risk
methyldopa	Fixed combination for initial hypertension management
methylene blue	Serotonin Syndrome with Concomitant Use of Serotonergic Drugs
methylphenidate	Tolerance and dependence
metoclopramide	Tardive Dyskinesia
metOLazone	Bolded (not boxed): do not interchange
metroNIDAZOLE	Carcinogenicity
mexiletine	Mortality; Acute Liver Injury
midazolam	Risk From Concomitant Use With Opiods; Individualize dose
midodrine	Supine blood pressure > 180 mmHg
milnacipran (non-formulary)	Suicidal ideation
minoxidil	Antihypertensive risk
mirtazapine	Suicidal ideation
mirvetuximab soravtansine	Ocular Toxicity
miSOPROStol	Pregnancy risk
mitoMYcin	Bone marrow suppression; hemolytic uremic syndrome
mitoXANTRONE	Cardiotoxicity; baseline neutrophil count; extravasation risk
montelukast	Serious Neuropsychiatric Events
morphine	Injection PreserveFree: 24-hour observation following epidural/intrathecal administration Controlled/Extended Release: Addiction, Abuse, and Misuse; Life-Threatening Respiratory Depression; Accidental Exposure; Neonatal Opioid Withdrawal Syndrome
moxifloxacin	Tendinitis, tendon rupture
multivitamin with iron	Iron overdose risk
multivitamin with iron and fluoride	Iron overdose risk
multivitamin, prenatal	Iron Overdose Risk
mycophenolate mofetil	Prior to initiation of therapy
mycophenolic acid	Embryofetal Toxicity, Malignancies, and Serious Infections
nabumetone	Cardiovascular; gastrointestinal risk
nadolol (non-formulary)	Avoid abrupt withdrawal
nalbuphine	Life-Threatening Respiratory Depression
naloxone-pentazocine	Addiction, Abuse, and Misuse; Life-Threatening Depression; Accidental Exposure; Neonatal Opioid Withdrawal Syndrome
naproxen	Cardiovascular; gastrointestinal risk
natalizumab	Progressive multifocal leukoencephalopathy (PML)
nefazodone (non-formulary)	Hepatotoxicity
nelarabine	Prior to initiation of therapy; neurologic events
neomycin	Neurotoxicity, nephrotoxicity, ototoxicity; general toxicity
nevirapine	Hepatotoxicity; dermal reactions; patient monitoring
niMODipine	Serious harm with IV administration of oral product
nirmatrelvir-ritonavir	Risk of Serious Adverse Reactions Due to Drug Interactions
norepinephrine	Extravasation risk
norethindrone	Risk of Cardiovascular Disease; Visual Abnormalities
nortriptyline	Suicidal ideation
obinutuzumab	Hepatitis B Virus Reactivation and Progressive Multifocal Leukoencephalopathy
ofatumumab	Hepatitis B Virus (HBV) Reactivation/Progressive Multifocal Leukoencephalopathy
OLANZapine	Mortality in elderly with dementia related psychosis
olmesartan (non-formulary)	ACE inhibitor pregnancy risk
olodaterol (non-formulary)	Asthma-Related Death
olodaterol-tiotropium (non-formulary)	Asthma-Related Death
omalizumab	Anaphylaxis
onabotulinumtoxinA	Distant spread of toxin effect
oxaliplatin	Anaphylactic-like reactions
oxandrolone	Peliosis hepatitis; Liver Cell Tumors; Blood Lipid Changes
oxazepam	Risks From Concomitant Use With Opioids
oxyCODONE	Oral solution: Risk of errors Controlled release: Abuse potential
oxyMORphone (non-formulary)	Abuse/diversion potential; drug dependence
oxytocin	Elective induction of labor
PACLitaxel	Prior to initiation of therapy
PACLitaxel protein-bound	Prior to initiation of therapy
paliperidone	Mortality in elderly patients with dementia related psychosis
panitumumab	Dermatologic toxicity; infusion reactions
PARoxetine	Suicidal ideation
patiromer	Binding to Other Oral Medications
pegcetacoplan	Serious Infections Caused By Encapsulated Bacteria
peginterferon alfa-2a	RISK OF SERIOUS DISORDERS
pegloticase	Anaphylaxis and Infusion Reactions
penicillAMINE	Toxicity risk
pentostatin	Prior to initiation of therapy
perampanel	Serious psychiatric and behavioral reactions
perflutren	Serious cardiopulmonary reactions
perphenazine	Elderly patients with dementia related psychosis
pertuzumab	Cardiomyopathy and Embryo-Fetal Toxicity
phenylephrine	Prior to initiation of therapy
phenytoin	Cardiovascular risk with rapid infusion
phytonadione	Severe reactions with IM and IV use
pimecrolimus topical (non-formulary)	Long-term safety
pimozide	Elderly patients with dementia related psychosis
pioglitazone	Congestive heart failure
piroxicam	Cardiovascular; gastrointestinal risk
polymyxin B sulfate	Parenteral use: nephrotoxicity, neurotoxicity, pregnancy risk
potassium phosphate-sodium phosphate	Acute Phosphate Nephropathy
pozelimab	Serious Meningococcal Infections
prasugrel	Bleeding risk
prazosin	Combination Not Used for Initial Therapy
primaquine	Prior to initiation of therapy
procainamide	Positive titers with chronic administration
prochlorperazine	Elderly patients with dementia related psychosis
progesterone	Cardiovascular disorders; breast cancer; probable dementia
promethazine	Patients < 2 years; severe tissue injury
propafenone	Mortality (CAST trial results)
propranolol	Avoid abrupt withdrawal
propylthiouracil	Severe liver injury; acute liver failure
protamine	Hypotension, pulmonary hypertension; risk factors described
prothrombin complex	Arterial and venous thromboembolic complications
QUEtiapine	Elderly patients with dementia related psychosis
quiNIDine	Active antiarrhythmic therapy may increase mortality
quiNINE (non-formulary)	No benefit in leg cramps; hematologic risks
raloxifene	Risk of VTE and death from stroke
ramipril (non-formulary)	Use in Pregnancy, Fetal Toxicity
ramucirumab	Increased Risk of Hemorrhage
rasburicase	Anaphylaxis; hemolysis; methemoglobinemia; uric acid measure interference
Ravulizumab	Serious Meningococcal Infections
remdesivir	Black Box Warning is for Use of Remdesivir to Treat COVID-19. Remdesivir Must Be Administered by Intravenous (IV) Infusion.
remifentanil	Addiction, Abuse, and Misuse
reslizumab	Anaphylaxis
RHo (D) immune globulin	Intravenous - Intravascular Hemolysis
ribavirin	Oral: Monotherapy; hemolytic anemia; teratogenicity Inhalation: Respiratory function deterioration
risperiDONE	Elderly patients with dementia related psychosis
ritonavir	Drug interaction risk
riTUXimab	Fatal infusion reaction; mucocutaneous reactions; progressive multifocal leukoencephalopathy; hep b reactivation
rivaroxaban	Premature discontinuation; spinal/epidural hematomas
rocuronium	Prior to initiation of therapy
romosozumab	Potential Risk of Myocardial Infarction, Stroke and Cardiovascular Death
sacituzumab govitecan	Neutropenia and Diarrhea
sacubitril-valsartan	Valsartan: ACE inhibitor pregnancy risk
salmeterol	Asthma Related Deaths
salsalate	Cardiovascular; gastrointestinal risk
saquinavir	Bioequivalency
selegiline	Suicidal ideation
sertraline	Suicidal ideation
sirolimus	Immunosuppression; liver or lung transplant patients
sodium nitroprusside	Cyanide toxicity; hypotension risk; dilute
sodium phosphate	Phosphate nephropathy
sotalol	Therapy initiation; renal impairment caution; product selection
spironolactone	Possible tumorigen
stavudine	Pancreatitis, lactic acidosis, hepatomegaly
streptomycin	Neurotoxicity; nephrotoxicity
streptozocin	Nephrotoxicity; experienced physician; mutagen
succinylcholine	Hyperkalemic rhabdomyolysis in infants or children
SUFentanil	Addiction, Abuse, and Misuse
tacrolimus	Lymphoma risk; infection related to immunosuppression
tacrolimus topical	Long-term safety
tagraxofusp	Capillary Leak Syndrome
talquetamab	Cytokine Release Syndrome and Neurologic Toxicity, including Immune Effector Cell-Associated Neurotoxicity Syndrome
tamoxifen	Women at high risk for breast cancer; women with DCIS
tapentadol (non-formulary)	Abuse potential; limitations of use
tarlatamab-dlle	Cytokine Release Syndrome and Neurologic Toxicity, including Immune Effector Cell-Associated Neurotoxicity Syndrome
teclistamab	Cytokine Release Syndrome and Neurologic Toxicity including Immune Effector Cell-associated Neurotoxicity Syndrome
telmisartan (non-formulary)	ACE inhibitor pregnancy risk
temazepam	Risks From Concomitant Use With Opioids
tenofovir	Lactic acidosis, severe hepatomegaly; hepB co-infection
terbutaline	Preterm labor (injectable and oral)
teriparatide	Boxed Warning removed 11/16/2020
terlipressin	Serious or fatal respiratory failure
testosterone	Secondary exposure to testosterone Testosterone undecanoate injection: POME reactions and anaphylaxis Testosterone enanthate: Blood Pressure Increases Testosterone undecanoate Capsule: Increase in Blood Pressure
thioridazine	QTc prolongation; elderly with dementia related psychosis
thiothixene	Elderly patients with dementia related psychosis
thrombin topical	Bleeding, thrombosis risk
thyroid desiccated	Treatment of obesity or weight loss
ticagrelor	Bleeding Risk
tigecycline	All cause mortality
tipranavir	Both fatal and nonfatal intracranial hemorrhage have been reported.
tisotumab vedotin	Ocular toxicity
tiZANidine	Bolded (not boxed): bioequivalence between products
tobramycin	Ototoxicity, nephrotoxicity risk with IV use
tocilizumab	Serious infections risk
tolvaptan	Initiation or re-initiation monitoring
topotecan	Bone marrow suppression
toremifene	QT Prolongation; avoid CYP3A4 Inhibitors
traMADol	Addiction, Abuse, and Misuse; Life-Threatening Depression; Accidental Exposure; Neonatal Opioid Withdrawal Syndrome; and Hepatotoxicity
trastuzumab	Cardiomyopathy; infusion reactions, pulmonary toxicity; teratogenicity
traZODone	Suicidal ideation
tretinoin	Acute promyelocytic leukemia; experienced physician
triazolam (non-formulary)	Risks From Concomitant Use With Opioids
trifluoperazine	Elderly patients with dementia related psychosis
umeclidinium-vilanterol	Vilanterol: Asthma-related death
valGANciclovir	Hematologic Toxicity; Impairment of Fertility; Fetal Toxocity; Mutagenesis & Carcinogenesis
valproic acid	Risk to children exposed in utero
valsartan	ACE inhibitor pregnancy risk
vancomycin	Risk of Embryo-Fetal Toxicity Due to Excipient Containing Products
varenicline	Serious neuropsychiatric events, monitoring and patient counseling
venetoclax	Tumor Lysis Syndrome
venlafaxine	Suicidal ideation
vilazodone	Suicidal ideation
vinBLAStine	IV use only; granulocytopenia; avoid extravasation
vinCRIStine	IV use only; dose liposomal product differently
vinorelbine	IV use only; granulocytopenia; avoid extravasation
vortioxetine	Suicidal Thoughts and Behaviors
warfarin	Serious bleeding risk
zidovudine	Hematological adverse events; myopathy; lactic acidosis; hepatomegaly
ziprasidone	Mortality in elderly with dementia related psychosis
zolpidem	Complex Sleep Behaviors

Pharmacy Phone Numbers

Our Lady of the Lake Regional Medical Center
225-765-4434
Our Lady of the Lake Children’s Hospital
225-374-1380
Our Lady of the Lake Ascension Hospital
225-647-5057
Our Lady of the Lake Assumption Community Hospital
985-369-4290
Our Lady of Angels Hospital
985-730-6789

Our Lady of Lourdes Hospital
337-470-2866
Our Lady of Lourdes Women and Children’s
337-470-5070
Our Lady of Lourdes Heart Hospital
337-470-1080
St. Dominic Jackson Memorial Hospital
601-200-6000
St. Francis Medical Center
318-966-3461