HIGH ALERT: Please review policy carefully.

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HYDROmorphone

HYDROmorphone
Brand names: Dilaudid, HYDROmorphone HYDROCHLORIDE
Form Strength ANAN ASMP LACH LALK LOHH LOLR LOWC SDSD SESE SFSF Formulary Status
LIQUID, ORAL 1 mg/mL              
SOLUTION, INJECTABLE 0.5 mg/0.5 mL; 1 mg/mL; 2 mg/mL; 10 mg/mL
TABLET, ORAL 2 mg; 4 mg    

VIEW MORE Opioid Agonists
CLASS
280808
High Alert Drug : Policy

Comments:

Hydromorphone for injection (e.g. syringes, vials, PCAs, etc) high-alert


Medications Approved for Automatic Therapeutic Interchange Dosage Conversion Guidelines
(Note:  “Therapeutic Interchange” should be placed in the order comments

Demerol Conversion

Meperidine (Demerol)

Morphine

Hydromorphone (Dilaudid)

12.5 mg

1 mg

0.25 mg

25 mg

2.5 mg

0.5 mg

50 mg

5 mg

1 mg

>75

Call

Call

Other doses (below 75 mg)

Round-down after converting using 0.13 multiplier.  Pharmacist may round-down to the nearest standard dose Morphine.

Round-down after converting using 0.02 multiplier.  Pharmacist may round-down to the nearest standard dose Dilaudid.

Formulary; restricted to use in prevention of drug-induced or blood product-induced rigors (e.g. amphotericin B, platelets) and treatment of post-op shivers.
PCA/IV/PO/IM use non-formulary for all other indications. Call provider and recommend above conversion.

Drug Name Common Side Effects
hydromorphone
  • dizziness, sedation
  • GI: nausea, vomiting, constipation
  • itching (pruritis), flushing

Last updated: Apr. 26, 2024


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