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HIGH ALERT: Please review policy carefully.
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HYDROmorphone
HYDROmorphone
Brand names: Dilaudid, HYDROmorphone HYDROCHLORIDE
| Form | Strength | ANAN | ASMP | LACH | LALK | LOHH | LOLR | LOWC | SDSD | SESE | SFSF | Formulary Status |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LIQUID, ORAL | 1 mg/mL | |||||||||||
| SOLUTION, INJECTABLE | 0.5 mg/0.5 mL; 1 mg/mL; 2 mg/mL; 10 mg/mL | |||||||||||
| TABLET, ORAL | 2 mg; 4 mg |
High Alert Drug
: Policy
Last updated: Apr. 26, 2024
- Black Box Warning: Injection: Respiratory depression risk; abuse potential
- Black Box Warning: Injection, High Potency: Opioid-tolerant patients only; Respiratory depression risk; abuse potential
- Black Box Warning: Oral, extended release: Opioid-tolerant patients only; overdose risk; abuse potential
- Black Box Warning: Oral, liquid & tablets: Abuse potential; respiratory depression; neonatal withdrawal; alcohol interaction
- Do Not Crush: Extended-release Tablet - Note: breaking, chewing, crushing, dissolving before swallowing or injecting could result in overdose
- Therapeutic Interchange: T.I.
- Do Not Tube-LALK
Hydromorphone for injection (e.g. syringes, vials, PCAs, etc) high-alert
Medications Approved for Automatic Therapeutic Interchange Dosage Conversion Guidelines
(Note: “Therapeutic Interchange” should be placed in the order comments
Demerol Conversion
Meperidine (Demerol)
Morphine
Hydromorphone (Dilaudid)
12.5 mg
1 mg
0.25 mg
25 mg
2.5 mg
0.5 mg
50 mg
5 mg
1 mg
>75
Call
Call
Other doses (below 75 mg)
Round-down after converting using 0.13 multiplier. Pharmacist may round-down to the nearest standard dose Morphine.
Round-down after converting using 0.02 multiplier. Pharmacist may round-down to the nearest standard dose Dilaudid.
Formulary; restricted to use in prevention of drug-induced or blood product-induced rigors (e.g. amphotericin B, platelets) and treatment of post-op shivers.
PCA/IV/PO/IM use non-formulary for all other indications. Call provider and recommend above conversion.