Meperidine for injection (e.g. syringes, vials, PCAs, etc) high-alert
Medications Approved for Automatic Therapeutic Interchange Dosage Conversion Guidelines (Note: “Therapeutic Interchange” should be placed in the order comments
Demerol Conversion
Meperidine (Demerol)
Morphine
Hydromorphone (Dilaudid)
12.5 mg
1 mg
0.25 mg
25 mg
2.5 mg
0.5 mg
50 mg
5 mg
1 mg
>75
Call
Call
Other doses (below 75 mg)
Round-down after converting using 0.13 multiplier. Pharmacist may round-down to the nearest standard dose Morphine.
Round-down after converting using 0.02 multiplier. Pharmacist may round-down to the nearest standard dose Dilaudid.
Formulary; restricted to use in prevention of drug-induced or blood product-induced rigors (e.g. amphotericin B, platelets) and treatment of post-op shivers. PCA/IV/PO/IM use non-formulary for all other indications. Call provider and recommend above conversion.
Restricted: meperidine (Demerol) is restricted to the prevention and treatment of drug-induced or blood product-induced rigors (e.g., amphotericin B, platelets) and treatment of postoperative shivering
Meperidine for injection (e.g. syringes, vials, PCAs, etc) high-alert
Medications Approved for Automatic Therapeutic Interchange Dosage Conversion Guidelines
(Note: “Therapeutic Interchange” should be placed in the order comments
Demerol Conversion
Meperidine (Demerol)
Morphine
Hydromorphone (Dilaudid)
12.5 mg
1 mg
0.25 mg
25 mg
2.5 mg
0.5 mg
50 mg
5 mg
1 mg
>75
Call
Call
Other doses (below 75 mg)
Round-down after converting using 0.13 multiplier. Pharmacist may round-down to the nearest standard dose Morphine.
Round-down after converting using 0.02 multiplier. Pharmacist may round-down to the nearest standard dose Dilaudid.
Formulary; restricted to use in prevention of drug-induced or blood product-induced rigors (e.g. amphotericin B, platelets) and treatment of post-op shivers.
PCA/IV/PO/IM use non-formulary for all other indications. Call provider and recommend above conversion.