October
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The following policies were reviewed and approved:
The following drug classes were reviewed:
Formulary Appeal Request:
Formulary Addition Request: none
Consent Agenda (previously reviewed):
Therapeutic Interchange (Automatic) Proposals:
Protocol Review: none
Antimicrobial Stewardship:
For details of the meeting, including class reviews and consent agendas, click here
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August
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The following policies were reviewed and approved:
- Pitocin Policy Approval- Oxytocin Policy represented, but it was approved at the last PT meeting but small changes were made.
- LA State Law states that Misoprostol will be a controlled medication, CIV beginning 10/1/24
The following drug classes were reviewed:
- Antigout Agents (92:16) (40:40)
- Rifamycins (8:12.28.30) (8:16.04)
- Phosphodiesterase-4 (PDE4) Inhibitors (92:36, 84:06.92, 84:92, 48:32)
- Antiparathyroid Agents (Calcimimetics) (68:24.04):
- Antihelmintics (8:08)
- Leukotriene Modifiers (48:10.24)
- Antilipemic Agents (24:06.05) (24:06.92)
- Antithyroid Agents (63:36.08)
- Hepatitis C Virus (HCV) Inhibitors (8:18.40.20, 8:18.40.24, 8:18.40.16)
- Plasma Volume Expanders (16:00, 40:12)
- Cardiac Drugs, Misc (24:04.92)
- Vasopressin Antagonists (40:28.28)
Formulary Appeal Request: Bevacizumab (Avastin) for intralesion/intralaryngeal injections for recurrent respiratory papillomatosis; studies showing safety and effectiveness only used the branded product. Will be outpatient only for specialized ENT procedures. In-hospital using biosimilar.
Formulary Addition Request: none
Consent Agenda (previously reviewed):
- Rabies Immune Globulin
- RhoD Immune Globulin
- Vitamin D analogs
- Potassium replacement products (oral)
- Potassium replacement products (IV)
- First Generation Antihistamines (4:04)
- Second Generation Antihistamines (4:08)
- Insulins (68:20.08)
- Probiotics
- Progestins
- Estrogens
- Opiate Agonists (28:08.08)
- Opiate Partial Agonists
Therapeutic Interchange (Automatic) Proposals: Phosphorus Binder Formulations Sucroferric Oxyhydroxide (Velphoro) chewable will be switched to Renvela TID with meals
Antimicrobial Stewardship: Azithromycin 3-day duration (pharmacy driven) Antibiograms Complete for 2023 1. Adult Urine/Non-Urine 2. Pediatrics Combined antibiogram 3. Trends in Susceptibility over 3 years Antibiotic usage was presented for LOLR, LOHH, and LOWC campuses.
For details of the meeting, including class reviews and consent agendas, click here
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June
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The following policies were reviewed and approved at WCH:
1) Misoprostol 2) Oxytocin Induction
The following drug classes were reviewed:
- Polymyxins (8.12.28.28)
- Anesthesia Gases (N/A)
- Post-menopausal Osteoporosis Treatments, non-bisphosphonates (92:24, 24:22, 64:24.08, 68:16.12)
- Opiate Antagonists (28:10)
- Azole Antifungals (UPDATE) (8:14.08)
- Amphotericin B (UPDATE) (8:14.28)
- Guanylate Cyclase-C (GC-C) Agonists (56:92)
- Central Alpha Agonists (24:08.16)
- Oxytocics (76:00) (56:28.28)
- PDE3 Inhibitors (20:12.14) (20:12.18) (24:04.08)
- Mydriatics, Ophthalmic (52:24)
- Dopamine (D2) Agonists, Ergot-derived (28:36.20.04)
- Miotics, Ophthalmic (52:40.20)
- Complement Inhibitors, C5 and C3 (92:21.08) - wording update
- Soliris is formulary restricted to outpatient use (not preferred) and inpatient use for atypical hemolytic uremic syndrome only.
- Ultomiris is formulary restricted to outpatient use only (preferred).
- Empaveli and Veopoz will be nonformulary.
- Somatostatin Analogs (68:29.04) - wording update
- Octreotide (regular) will be formulary.
- Octreotide acetate LAR will be formulary-restricted to outpatient and in conjunction with Lutathera administration in same day admissions ONLY
- Lanreotide will be formulary-restricted to outpatient use only.
- Pasireotide will be non-formulary.
Formulary Appeal Request: Advair and Symbicort at the system level, not to be affected in Acadiana. Acadiana marked will continue to use nebs, not inhalers.
Formulary Addition Request: none
Consent Agenda (previously reviewed):
- PAMORA: GI Drugs, Misc (56:92)
- Surfactant (48:36)
- Selective Serotonin Agonists (28:32.28)
- Fibric Acid Derivatives (24:06.06)
- Cephalosporins (8:12.06)
- Add cefpodoxime; restrict cefdinir to patients < 2 months of age.
- Keep ceftazidime formulary but remove restriction criteria
- Penicillins (8:12.16)
- Penicillin g sodium will be formulary.
- Aminoglycosides (8:12.02)
- Fluoroquinolones (8:12.18)
- Carbapenems (08:12.07.08)
- Remove meropenem/vaborbactam from formulary
- Magnesium Replacement Products
- Phosphate Binders (40.18.19)
- Oral Iron Replacement
- Ferrous sulfate tablets, enteric coated tablets, and suspension oral liquid will be formulary.
- Ferrous sulfate extended-release tablets, ferrous gluconate, ferrous fumarate, iron polysaccharide complex, and ferric maltose will be non-formulary.
- For ferric citrate formulary status see Phosphate Binder Class Review.
- SNRIs
- SSRIs
- 5-ASA Derivatives (56:36)
- Prostacyclin (48:48)
- Potassium-Removing Agents (40:18.18)
- AntiMRSA Antibiotics (8:12.28)
- Tetracyclines (8:12.24)
- Monobactam (8:12.07.16)
- Sulfonamide (8:12.20)
- Lincosamide (8:12.28.20)
- Antibacterials, Misc - Nitroimidazoles (8:12.28)
- Macrolides (8:12.12)
Therapeutic Interchange (Automatic) Proposals:
Inhalers to Nebs
- Steroid/beta blocker combos -> albuterol + budesonide
- Anticholinergic/beta bocker combos -> albuterol + ipratropium
- Steroid/beta blocker/anticholingeric combos -> albuterol + ipratropium with budesonide
- Long acting anticholinergics -> Ipratropium
- Beta Blockers -> albuterol
Thiamine IV to PO per protocol
Omnicef removal from formulary to Augmentin or Vantin
Ophthalmic Fluoroquinolones
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- Cipro ointment to erythromycin ointment
- FQ Ophthalmic solutions to Ofloxacin
Protocol Review: none
Antimicrobial Stewardship: Review of 2024 Q1 usage at all three campuses
For details of the meeting, including class reviews and consent agendas, click here
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April
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Burn Fluid Order Set was updated at MEC and taken to local P&T.
Policy PCS-378: Peripheral Parenteral Nutrition was reviewed and discussed
The following drug classes were reviewed:
- Antidiarrheal agents
- Alpha-glucosidase inhibitors
- GLP-1 receptor agonists
- Bile acid sequestrants
- Scabicides/pediculicides
- Barbiturates: updated to include pentobarbital
- Nucleoside Reverse Transcriptase Inhibitors
- Vemlidy (tenofovir/alafenamide) added for Hep B patients
- Alpha-adrenergic blocking agents:
- Prazosin with restriction to use by psych in PTSD & nightmares
- Protease Inhibitors: Keletra (lopinavir/ritonavir) oral solution will be restricted to peds
- Anticonvulsants Succinimide: Ethosuximide oral suspension will be restricted to peds.
- Botulinum Toxins (92:92)
- Alpha-1 Proteinase Inhibitors (48:92)
- Asthma Biologics (48:10.20, 48:92)
- Neuraminidase Inhibitors (8:18.28, 8:18.92)
- Complement Inhibitors:
- Angioedema Treatment (92:32)
- Complement Inhibitors, C5 and C3 (92:21.08)
Formulary Appeal Request: none
Formulary Addition Request: none
Consent Agenda (previously reviewed):
- Antihemorrhagic Agents: Andexxa
- Praxbind (20:28.92)
- Loop Diuretics (24:08.24.08)
- Thiazide Diuretics (24:08.24.20)
- Diuretics, misc (24:08.24.92)
- Calcium Channel Blockers
- Non-Dihydropyridine (24:28.92)
- Calcium Channel Blockers, DHP (24:28.08)
- Benzodiazepines (28:12:08)
- Alpha-Adrenergic Blocking Agents (24:08.4)
- 5-alpha Reductase Inhibitors (92:08)
- Antivirals, topical (84:04.06)
- Nucleoside Reverse Transcriptase Inhibitors (NRTIs) (8:18.08)
- Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) (8:18.08)
- Protease Inhibitors (PIs) (8:18.08)
- Integrase Inhibitors (8:18.08)
- Entry Inhibitors (8:18.08)
- Fixed-dose Combinations (8:18.08)
- Anticonvulsants Pyrrolidine (28:12.92)
- Anticonvulsants Succinimide (28:12.20)
- Anticonvulsants Valproates (28:12.92)
- Anticonvulsants Misc 2 (28:12.92)
- Anticonvulsants Misc 3 (28:12.92)
- Angiotensin II (Giapreza)
- Remdesivir (Veklury)
- Rolvedon: restricted to outpatient use only
- Surfactants (simethicone)
- Ophthalmic Agents: NSAIDS
- Ophthalmic Agents: Mast Cell Stabilizers
- Ophthalmic Agents: Beta Blockers
- Ophthalmic Agents: Prostaglandins
- Ophthalmic Agents: Alpha2 Agonists
- Ophthalmic Agents: Carbonic Anhydrase Inhibitors
- Ophthalmic Agents: Combo Products
- Hemostatic: Factor VII (20:28.16)
- Hemostatic: Factor VIII (20:28.16)
- Hemostatic: Factor IX (20:28.16)
- Hemostatic: von Willebrand Factor (20:28.16)
- Beta Blockers (24:24)
- Intranasal Steroids (52:08.08)
- Inhaled Corticosteroids (68:04)
- Selective Beta-2-Adrenergic Agonists (48:12.04.12)
- Anticholinergic Agents (48:12.08)
Therapeutic Interchange (Automatic) Proposals:
Kcentra to Balfaxar Conversion: will proceed in EPIC on April 2nd, 2024
Biosimilar Interchanges (Inpatient):
- Avastin Interchange (to Zirabev)
- Herceptin Interchange (to Ogivri)
- Neulasta Interchange (to Fulphila)
- Neupogen Interchange (to Granix)
- Remicade Interchange (to Renflexis)
- Rituxan Interchange (to Ruxience)
Protocol Review: none
Antimicrobial Stewardship: CRRT/SLED Antimicrobial Dosing Guidelines
For details of the meeting, including class reviews and consent agendas, click here
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February
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The following was clarified: Infliximab-abda (Renflexis) will be the formulary product for inpatient use if needed . Truxima will be used instead of Rituxan.
The following drug classes were reviewed:
- 4 Factor PCC
- Balfaxar will be formulary, replacing KCentra
- Aromatase Inhibitors
- Estrogen Receptor Antagonists
- Antigonadotropins
- Gonadotropin Releasing Hormone (GnRH) Agonists
- Lupron Depot available via the non-formulary process for patients with Prostate Cancer with spinal metastasis
- Gonadotropin Releasing Hormone (GnRH) Agonists, Other
- CGRP antagonists
Formulary Appeal Request:
Trihexphenidyl Liquid was approved for use in pediatrics.
Formulary Request:
Cefiderocol (Fetroja): was presented and approved for the use in Multi-Drug Resistant Organisms with the restriction to ordering by
1. Infectious Disease Providers only
2. Critical Care providers if a facility does not have an ID provider.
Consent Agenda (previously reviewed):
- Anticonvulsants Hydantoin (28:12.12)
- Anticonvulsants Barbiturates (28:12.04)
- Anticonvulsants Dibenazapine (28:12.92)
- Anticonvulsants GABA (28:12.92)
- Anticonvulsants Misc 1 (28:12.92)
- Antiparkinsons agents MOAB inhibitors (28:36.32)
- Antiparkinsons agents Misc (28:92) and (28:36.08)
- Antiparkinsons agents COMT inhibitors (28:36.12)
- Antiparkinsons agents Dopamine agonists (28:36.04) and (28:36.20.08)
- Ophthalmic Antimicrobials, fluoroquinolones (52:04.04)
- Bone Resorption Inhibitors (92:24)
- P2Y12 Inhibitors (20:12.18)
- Calcitonin
- ACE-Inhibitors (24:32.04)
- Angiotensin Receptor Antagonists (24:32.08)
- HMG Co-A Reductase Inhibitors (24:06.06)
- Proton-Pump Inhibitors (56:28.36)
- 5-HT3 Receptor Antagonists (56:22.20)
- Gleolan
Therapeutic Interchange (Automatic) Proposals:
- Topical Antifungals
- Moduretic to Dyazide
Antimicrobial Stewardship
Antibiotic usage was presented for LOLR, LOHH, and LOWC campuses.
For details of the meeting, including class reviews and consent agendas, click here
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