Max single IV bolus dose = 20 mg at any given time (whether an infusion is being started or not).
diltiaZEM should generally not be interrupted during procedures unless there is a specific physician order.
Refrigerator item (injection)
Per policy, these medications require cardiac and/or special monitoring. (KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
generic (Brand) / Notes
diltaZEM (Cardizem) IV Push, IV Infusion
Y
Y
N
N
N
N
N
N
Iredell Memorial Hospital ICU Adult Infusion Guidelines
The following orders are intended to provide a specific, safe, and effective means of initiating and titrating medications for critically ill patients. Physicians may modify doses and/or parameters as necessary pending patients' status.For all medications listed below, the responsible LIP is to be notified if unable to titrate or the maximum dose is reached andgoals of therapy are not met.
Drug Name
Onset
Preparation
Compatible fluids
diltiaZEM (Cardizem)
minutes
125 mg/100 ml fluid for total volume of 125ml. Concentration = 1mg/ml
NS or D5W
Starting Dose for ICU Sedation
Titration Guidelines (for increasing and decreasing doses) with Maximum dose
LD: 0.25 mg/kg over 2 min. Max = 20 mg. Begin infusion at 5 mg/hr.
titrate by 5 mg/hr every 15 min to goal heart rate of ≤ 110 beats per min or conversion to normal sinus rhythm, whichever comes first. Max = 15 mg/hr.
Per policy, orders for these non-formulary agents will be changed to formulary equivalents.
Non-Formulary Agent
Formulary Equivalent
diltiaZEM BID products
diltiaZEM SR (Cardizem SR)
diltiaZEM once daily products
diltiaZEM CD (Cardizem CD)
Enteral Drug Administration notes.
Generic (Brand)
Comments and Considerations
Recommendations for Administration with Enteral Nutrition
diltiaZEM (Dilacor, Tiazac, Cardizem)
Food increases absorption by 28%.
Suggest dividing total daily dose into immediate release tables every 6-8 hours
diltiaZEM (Dilacor, Tiazac, Cardizem)
May open Tiazac capsule but do NOT crush the contents
Tiazac capsule may be opened contents may be emptied into feeding tube, but do NOT crush contents.
Last updated: May. 1, 2024
Look-Alike/Sound-Alike diltiaZEM confused with diazePAM
Refrigerator item (injection)
(KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
IV Push, IV Infusion
(Brand)
(Dilacor, Tiazac, Cardizem)
(Dilacor, Tiazac, Cardizem)