Medications not yet evaluated by P&T are considered NON-FORMULARY . . . . . Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step! . . . . . Please be sure to document all clinical activities daily.
P & T Update Memo February 2017

Following is a P and T Committee update (from the February 28th meeting). Starting date for specific programs is 6 March 2017, unless otherwise noted. Please let me know if you have any questions or comments. Don’t forget to check the “New Drug Monitoring Spotlight” section of the website, which provides important monitoring information about newly approved drugs. Also, attached is the updated version of the “Not Stocked, Not Ordered” drug list with the new additions highlighted in red. 

Below is the memo with links to the drug monographs, protocols, and formulary documents. Click to access the full P&T packet for this month, or here to access the P&T packet archive.

Drug or Drug Class

Formulary Decision

Comments

lisinopril liquid (Obrelis)

Formulary, Restricted

Use restricted to pediatric patients. If needed, a liquid suspension of lisinopril can be prepared until the commercially available solution can be obtained.

budesonide nasal spray (Rhinocort Allergy)

 

Non-Formulary Automatic Interchange Approved

 

Interchange to fluticasone propionate 50 mcg nasal spray at the same dosing interval.

Niacin / Niacinamide Products

 

Niacinamide: Formulary (100 mg, 500 mg)

Niacin IR: Formulary (250 mg, 500 mg)

Niacin ER: Formulary (250 mg, 500 mg, 750 mg)

 

Other Niacinamide/Niacin

Formulations: Non-Formulary

 

Automatic Interchanges Approved

Several niacinamide and niacin dosage strengths were classified as nonformulary.

Pharmacists may dose round or divide daily ER doses to IR in BID or TID regimens to achieve similar total daily dosage with available formulary strengths.

 

edoxaban (Savaysa) Update

 

Formulary, Restricted

 

Automatic Interchange Approved

 

Edoxaban has been very low use – use restricted to orders specifying no substitution or patients taking edoxaban as a home medication when interchange to apixaban during admission is judged to be of higher risk.

 

Automatic interchange to apixaban was approved utilizing specified guidelines based on indication and drug interactions.

 

edoxaban is not routinely stocked.

sotalol IV Update

Non-Formulary

Prescriber should be contacted to discuss alternative agents (ex. amiodarone, procainamide, or lidocaine)

 

rucaparib (Rubraca)

Non-Formulary

Oral oncology agent, patients may use home supply.

altretamine (Hexalen)

Non-Formulary

Oral oncology agent, patients may use home supply.

granisetron ER inj. (Sustol)

 

Non-Formulary, Automatic Interchange Approved

 

Automatic interchange to ondansetron 16 mg PO or IV.

lipid emulsion (SMOFlipid)

 

Formulary, Restricted

Restricted to use in neonatal patients.

May be advantage in patients with PNALD and IFALD.

eculizumab (Soliris)

Formulary, Restricted

Restricted to oncology and nephrology strictly following approved criteria set. Reviewed by High Impact Committee. Criteria for use approved.

Defibrotide (Defitelio)

Non-Formulary

This drug will not be used at Huntsville Hospital, reviewed by High Impact Committee.

Atezolizumab (Tecentriq)

Formulary, Restricted

Use restricted to oncology in the outpatient setting. Some use in oncology outpatient setting expected, reviewed by High Impact Committee. 

Allopurinol Renal Dose Adjustment Update

Dosing Adjustment Update Approved

Based on newer guidelines. Will be updated in Sentri7 and Pharmacist Quick Reference Guide.

Anti-Infective Renal Dose Adjustment Update

Dosing Adjustment Updates

Approved: AZTreonam, ceFAZolin, and oseltamivir

Based on newer guidelines. Will be updated in Sentri7 and Pharmacist Quick Reference Guide.

alvimopan (Entereg) Discontinuation with Bowel Movement

Protocol Addition Approved

Includes discontinuation of alvimopan at first bowel movement in all patients.

Electrolyte Protocol Update - Adults

 

Protocol Addition Approved

Allows the prescriber to select all four electrolyte repletion regimens (potassium, magnesium, calcium, and phosphorus) or any combination of the four. Updated procedures for each of the above electrolytes. Pending review from other institutional committees. Additional education to follow.

Pediatric Dose Standardization Update

 

80 mg acetaminophen suppository and 6 mg oral prednisoLONE dose both added to program and approved by Pediatric Subcommittee

 

Both will improve accuracy of pediatric dosing.

Pediatric Nebulization Protocol Update

 

Protocol Updates Approved by Pediatric Subcommittee

Racemic epinephrine and dexamethasone added, and formatting simplified.

Pediatric Taper/Titration Guideline Update

Protocol Updates approved by Pediatric Subcommittee

 

Changes made to reflect recent changes in adult guidelines, including propofol.

Daptomycin MUE

Results reviewed by ID Subcommittee, 53% of cases did not meet approved criteria.

Follow-up educational activities planned through AMT

Pre-op Colon Surgery Antibiotic Guidelines

 

ID Subcommittee Recommended Specific Guidelines

Recommendations were to use cefOXitin as antibiotic of choice instead of ertapenem, and use the combination of levoFLOXacin and metroNIDAZOLE if patient had serious allergy to penicillin.

Oncology Subcommittee

Informational: First Meeting held earlier in February

Organizational and formulary issues addressed

 

 






This site is intended for the staff of Huntsville Hospital.
While others may view accessible pages, Huntsville Hospital makes no warranty, express or implied,
as to the use of this information outside of Huntsville Hospital.
Please note than many documents are accessible via the provided link
only when connected to the Huntsville Hospital intranet.