Following is a P and T Committee update (from the September 25th meeting). Starting date for specific programs is 1 Oct 2018, unless otherwise noted. Please let me know if you have any questions or comments. Don’t forget to check the “New Drug Monitoring Spotlight” section of the website, which provides important monitoring information about newly approved drugs. Also, attached is the updated version of the “Not Stocked, Not Ordered” drug list with the new additions highlighted in red.
Below is the memo with links to the drug monographs, protocols, and formulary documents. Click to access the full P&T packet for this month, or here to access the P&T packet archive.
Drug or Drug Class |
Formulary Decision |
Comments |
fostamatinib (Tavalisse) | Non-Formulary | Inpatients may use own supply. |
ivosidenib (Tibsovo) | Non-Formulary | Inpatients may use own supply. Defer initiation until after hospital discharge. |
axicabtagene ciloleucel (Yescarta) | Non-Formulary | Initiation of therapy must be done at an approved, certified regional site. |
Pertuzumab (Perjeta) | Referred to High Value Care Committee | If approved, use will be restricted to outpatient infusion areas. |
filgrastim-aafi (Nivestym) |
Formulary
|
An expanded automatic interchange among filgrastim agents based on economic considerations was approved. Pediatric use pending as St. Jude has not yet evaluated the new biosimilar. |
Aripiprazole lauroxil (Aristada Intio) | Formulary, Restricted | Restricted to use by psychiatry utilizing a no-charge dose initiation program sponsored by the drug company. |
apentadol (Nucynta & Nucynta ER) | Formulary | Reclassified as formulary due to increased utilization in the community and classification as a controlled substance, schedule II. |
Insulin human, injection 500 units/mL (Humulin R U-500) |
PEN: Formulary, Restricted
|
Restricted to continuation of home
|
Aristada Order Set | Order Set Approved | Build in Cerner pending. |