Approved Hospital Formulary
Add Formweb to your mobile device
Approved Hospital Formulary
P & T Update Memo December 2017
Following is a P and T Committee update (from the December 12th meeting). Starting date for specific programs is 18 December 2017, unless otherwise noted. Please let me know if you have any questions or comments. Don’t forget to check the “New Drug Monitoring Spotlight” section of the website, which provides important monitoring information about newly approved drugs. Also, attached is the updated version of the “Not Stocked, Not Ordered” drug list with the new additions highlighted in red.
Below is the memo with links to the drug monographs, protocols, and formulary documents. Click to access the full P&T packet for this month, or here to access the P&T packet archive.
|
Drug or Drug Class |
Formulary Decision |
Comments |
| meropenem-vaborbactam (Vabomere) | Formulary, Restricted Automatic Renal Adjustment | Restricted to use by infectious disease physicians for carbapenem resistant enterobacteriacea (CRE) in cases when the patient has a severe penicillin/cephalosporin allergy or a documented resistance to Avycaz. Automatic renal adjustments by pharmacists approved. |
| glecaprevir-pibrentasvir (Mavyret) | Non-Formulary | Non-Formulary. Initiation should be deferred until after hospital discharge. Inpatients may use their own supply. |
| sofosbuvir-velpatasvir-voxilaprevir (Vosevi) | Non-Formulary | Non-Formulary. Initiation should be deferred until after hospital discharge. Inpatients may use their own supply. |
| cerliponase alfa (Brineura) | Non-Formulary | Utilized for the treatment of late infantile neuronal ceroid lipofuscinosis type 2 (CLN2). Very rare use is expected. Patients requiring therapy would likely be referred to academic medical center. |
| belimumab subcutaneous (Benlysta) | Non-Formulary | Non-Formulary. Initiation should be deferred until after hospital discharge. Inpatients may use their own supply. The IV formulation remains formulary, restricted. |
| sarilumab (Kevzara) | Non-Formulary | Non-Formulary. Initiation should be deferred until after hospital discharge. Inpatients may use their own supply. |
| Calcium gluconate tablet Shortage/Discontinuation | Non-Formulary | Oral calcium gluconate served as the formulary work horse for the low potency calcium supplements. It is no longer manufactured. An automatic interchange to calcium carbonate 500 mg (200 mg elemental calcium) was approved for all low-potency calcium supplements. |
| Folic Acid IV Interchanges – Small Volume IVF Shortage | Automatic Conversion to IVP or PO Approved | Orders for folic acid IVPB may be automatically interchange to IVP (over ≥ 1 min) or PO/enteral administration if IV-to-PO conversion criteria are met. |
| Thiamine IV Interchange – Small Volume IVF Shortage | Discussed | Automatic conversion was discussed but tabled for further discussion at this time. Pharmacists should continue to contact prescribers to determine if PO thiamine is appropriate. In addition to oral administration, alternatives to thiamine IVPB to recommend include: addition to larger volumes of IVF (250 – 1000 mL) if not required emergently or IM administration |