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Following is a P and T Committee update (from the October 25th meeting). Starting date for specific programs is 1 November 2017, unless otherwise noted. Please let me know if you have any questions or comments. Don’t forget to check the “New Drug Monitoring Spotlight” section of the website, which provides important monitoring information about newly approved drugs. Also, attached is the updated version of the “Not Stocked, Not Ordered” drug list with the new additions highlighted in red.
Below is the memo with links to the drug monographs, protocols, and formulary documents. Click to access the full P&T packet for this month, or here to access the P&T packet archive.
|
Drug or Drug Class |
Formulary Decision |
Comments |
| brigatinib (Alunbrig) | Non-Formulary |
Inpatients should use their own supply. Defer initiation until after discharge. |
| methotrexate (Xatmep) Oral Solution | Non-Formulary | Inpatients may use own supply. Huntsville Compounding may be utilized if a liquid preparation is required for an inpatient without a home supply. |
| midostaurin (Rydapt) | Formulary, Restricted | Restricted to Oncology use for low-income inpatients requiring induction therapy. Inpatients may use own supply; a prescription may be filled by CCI or HH Outpatient Pharmacy. |
| panitumumab (Vectibix) | Formulary, Restricted | Restricted to Oncology use in the outpatient setting. |
| durvalumab (Imfinzi) | Formulary, Restricted | Restricted to Oncology use in the outpatient setting. |
| poractant (Curosurf) | Formulary, Restricted | A pilot study completed at HH W&C neonatal ICU demonstrated notably less bradycardia with Curosurf. Curosurf is restricted to neonatalology. |
| calfactant (Infasurf) | Non-Formulary | A benefit in the safety profile of an alternative product, Curosurf, was demonstrated during a pilot study. Infasurf was reclassified as nonformulary. |
| amphetamine salts (Mydayis) | Non-Formulary Therapeutic Interchange Approved |
Orders for Mydayis will be automatically interchanged to dextroamphetamine/amphetamine ER product at similar strengths. |
| methylphenidate (Cotempla XR-ODT) | Non-Formulary Therapeutic Interchange Approved |
Orders for Cotempla will be automatically interchanged to methylphenidate ER at an equivalent strength. |
| acetaminophen Intravenous (Ofirmev) – CV Surgery | Ofirmev - No Changes Deferred to Medical Executive Committee and High Impact Committee |
Further use of intravenous acetaminophen pending input from Medical Executive and High Impact Committees. |
| sodium bicarbonate IV shortage update | Informational | Intravenous sodium bicarbonate remains on national shortage. The Medical Executive Committee will be evaluating use within the institution and appropriate indications as the shortage resolves. |
| codeine / traMADol restrictions update | Formulary, Restricted to Adult Patients Not Currently Breast Feeding | Codeine and tramadol is restricted to patients ≥ 18 years of age. The Committee approved expanding the restrictions to avoid use in breastfeeding mothers due to possible harm to their infants. |