Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances. The following outlines must be followed.
generic (Brand) Route [Packaging: Mfg ⇒ Dispense]
NIOSH Group
voriconazole (Vfend) PO [UD ⇒ UD]
Reproductive Risk
Pharmacy: Receiving / Storage / Preparation
Exposure Risk: minimal
• Handling/preparation PPE Requirements: n/a
• Receiving from Distributor: Standard
• Pharmacy Storage Area: Carousel
• Packaging/Reconstitution Location: n/a
• Compounding (Non-Sterile/Sterile) Location: n/a
• Omnicell Load: No
Transport
• Transport (dose is placed inside a plastic sealable bag): Standard
Nursing: Storage / Admin.
Exposure Risk: low
• Handling/administration PPE Requirements: PO- Single CX gloves , tube- double CX gloves and gown , wash hands after handling
• Storage of Finished dose in Nursing Area/Procedural Area: Patient Med Drawer
• Signage on Patient Door Required: No
• Manipulation of Dosage Form: Standard
• Special Manipulation for Administration: n/a
Disposal / Spills
• Disposal of Drug Waste: Full- blue bin , trace/packaging- trash
• Disposol of Used PPE: trash bin (inside plastic bag)
• Spill management: n/a
Reason for exemption of USP<800> Containment Requirements: Purchased in final dosage form; packaged as unit dose. Does not require additional manipulation for dispensing.
Enteral Drug Administration notes.
Generic (Brand)
Comments and Considerations
Recommendations for Administration with Enteral Nutrition
voriconazole (Vfend)
AUC decreased by 22% when taken with food.
Suggest holding tube feeding 1 hour before and 1 hour after administration
Last updated: Apr. 17, 2024
Renal Adjustment Policy voriconazole subject to adjustments by pharmacy.
Hazard.Drug Handling(USP 800) USP<800> Hazardous Drug / Assessment of Risk
(Brand)
• Indications
Comments
(Vfend©)
200 mg q12h
Wt < 40 kg:
100 mg q12h
The following outlines must be followed.
Receiving /
Storage /
Preparation
minimal
Storage /
Admin.
low
Spills
(Brand)
(Vfend)