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voriconazole IV

voriconazole IV

Brand names: Vfend

Form	Strength
POWDER FOR INJECTION, INTRAVENOUS	200 mg

Display Azoles Class: 081408

Medication comments:

voriconazole should be dosed using Adjusted Body Weight for obese patients with BMI >30 kg/m².

Per policy, these drugs are subject to renal dosing adjustments by pharmacy.
Generic + Route (Brand) • Indications	Usual Adult Dose Comments	Renal Dosage Adjustments
voriconazole IV (Vfend^©)	6 mg/kg q12h x 2 doses, then 3-4 mg/kg q12h	No adjustment necessary

Per policy, these drugs may be converted from IV to PO in patients who meet criteria.
voriconazole (Vfend) IV	weight based dosing (3-4 mg/kg q12h)	200 mg PO q12h
voriconazole (Vfend) IV	fixed (non-weight based) dosing	may convert from IV to PO on a mg-to-mg basis.

USP <800> Hazardous Drug Assessment of Risk (AOR)
Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances. The following outlines must be followed.
generic (Brand) Route [Packaging: Manufacturer ⇒ Dispense]		NIOSH Group
voriconazole (Vfend) IV [n/a]		Reproductive Risk
Pharmacy: Receiving / Storage / Preparation Exposure Risk: low	• Handling/preparation PPE Requirements: Double CX gloves , gown , CSTD
	• Receiving from Distributor: Standard
	• Pharmacy Storage Area: IV CSTD Area
	• Packaging/Reconstitution Location: n/a
	• Compounding (Non-Sterile/Sterile) Location: Ideal: Positive pressure room Required: Med Prep Area with Immediate Use Preparation standards
	• Omnicell Load: No
Transport	• Transport (dose is placed inside a plastic sealable bag): Double bag, single CX gloves
Nursing: Storage / Admin. Exposure Risk: low	• Handling/administration PPE Requirements: Single CX glove, gown , use of CSTD
	• Storage of Finished dose in Nursing Area/Procedural Area: Picked up from Pharmacy
	• Signage on Patient Door Required: Yes
	• Manipulation of Dosage Form: n/a
	• Special Manipulation for Administration: n/a
Disposal / Spills	• Disposal of Drug Waste: Full- black bin , trace- yellow bin
	• Disposol of Used PPE: yellow bin
	• Spill management: Manage like antineoplastic agents
Reason for exemption of USP<800> Containment Requirements: Preg Category D. Release to the environment should be minimized per MSDS.

Last updated: Apr. 4, 2024

Renal Adjustment Policy voriconazole subject to adjustments by pharmacy.
Hazard.Drug Handling(USP 800) USP<800> Hazardous Drug / Assessment of Risk
IV to PO Conversion Policy Policy

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556

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as to the use of this information outside of Iredell Memorial Hospital.
The content of this policy and procedure document serves as guidance to the delivery of quality patient care.
Care providers are expected to exercise critical thinking and situational awareness skills,
and in specific situations to take such action as is necessary for the delivery of quality patient care.