• Stored separately in pharmacy. • Drugs are transported in plastic bags/designated transport containers labeled with sticker indicating CHEMOTHERAPY DRUG.
Per policy, these hazardous drugs have special waste requirements.
Generic (Brand)
Waste Requirements
vismodegib (Erivedge)
If > 3% by weight of drug remains ⇒ BLACK BUCKET Trace amounts/uncontaminated PPE ⇒ YELLOW BUCKET
USP <800> Hazardous Drugs
Per Policy, these drugs have special handling requirements (any drug with an "AOR" is exempt from these requirements under normal circumstances).
generic (Brand) Route
Relative Risk Level
AOR?
NIOSH 2024 Table
MSHI?↑
Warnings
vismodegib (Erivedge) PO
Low
N/A
2B↑
NIOSH Supplemental information (2016): Black Box warning on embryo-fetal death or severe birth defects; recommend effective contraception for females during therapy and for 7 months after treatment; present in semen; no sperm donation during and 3 months post treatment FDA Pregancy Category D: There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks;
Last updated: Jun. 5, 2025
Hazard.Drug Handling(USP 800) USP<800> Hazardous Drug
• Drugs are transported in plastic bags/designated transport containers labeled with sticker indicating CHEMOTHERAPY DRUG.
Trace amounts/uncontaminated PPE ⇒ YELLOW BUCKET