Note: use 10 day stop date for oral vancomycin given for C.diff infections.
Vancomycin preop dose order comments:
***ON CALL*** Give vancomycin 1 gm for weight less than 80 kg (176 lbs) or 1.5 gm for weight 80 kg or more. Give in Holding Room.
Per policy, orders for these non-formulary agents will be changed to formulary equivalents.
Non-Formulary Agent
Formulary Equivalent
vancomycin oral any strength/frequency
Convert oral doses to 125 mg q6h x 10 days. If 500 mg ordered, evaluate whether appropriate per protocol for fulminant infection (hypotension, shock, ileus, or megacolon). If these criteria not met, change to 125 mg po q6h x 10 days.
Adult Extravasation Management
vancomycin (Vancocin)
Agent type:
Non-Chemotherapeutic
Vesicant/Irritant:
Irritant
Local Care:
Warm or cold compress
Antidote:
Hyaluronidase
Antidote link(s):
Last updated: Jun. 18, 2025
Therapeutic Interchange Policy Oral dose limit = 125 mg q6h x 10 days
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