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valproic acid IV

valproic acid IV

Brand names: Depacon

Form	Strength
SOLUTION, INTRAVENOUS	100 mg/mL

Display Anticonvulsants, Miscellaneous, Antimanic Agents, Antimigraine Agents, Miscellaneous Class: 281292, 282800, 283292

Medication comments:

Per policy, these medications require cardiac and/or special monitoring. (KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
generic (Brand) / Notes	CCU, OR, PACU, CCL, ED	PCU	2N (Tele)	1N (Tele), 3N (Tele)	Med/Surg (1N w/o Tele, 3N w/o Tele, 4N, 5N)	BirthPlace	SNF	ICS	OPS
valproic acid (Depacon) IV Push,IV Infusion	Y	Y	Y	Y	Y	Y	Y	Y	Y

USP <800> Hazardous Drug Assessment of Risk (AOR)
Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances. The following outlines must be followed.
generic (Brand) Route [Packaging: Manufacturer ⇒ Dispense]	Activities
valproic acid (Depacon) IV [n/a]		Stock @ IDBH? N NIOSH Table 2^↑
Pharmacy: Receiving / Storage / Preparation Exposure Risk: low	• Handling/preparation PPE Requirements: Single CX glove, gown Do not prepare if pregnant.
	• Receiving from Distributor: Standard
	• Pharmacy Storage Area: IV Area
	• Packaging/Reconstitution Location: n/a
	• Compounding (Non-Sterile/Sterile) Location: Positive pressure room
	• Omnicell Load: No
Transport	• Transport (dose is placed inside a plastic sealable bag): Standard
Nursing: Storage / Administration Exposure Risk: low	• Handling/administration PPE Requirements: Single pair of CX approved gloves. Wash hands after handling
	• Storage of Finished dose in Nursing Area/Procedural Area: Patient Med Drawer
	• Signage on Patient Door Required: No
	• Manipulation of Dosage Form: n/a
	• Special Manipulation for Administration: n/a
Disposal / Spills	• Disposal of Drug Waste: Full- black bin Trace- yellow bin
	• Disposol of Used PPE: trash bin (inside plastic bag)
	• Spill management: n/a
NIOSH Supplemental Information: BBW for teratogenicity; congenital malformations, including neural tube defects; teratogenic in multiple species
Reason for exemption of USP<800> Containment Requirements: Preg Category D. Risks are related to systemic absorption. Skin contact - wash immediately with soap and water.

Last updated: May. 22, 2025

Hazard.Drug Handling(USP 800) USP<800> Hazardous Drug / Assessment of Risk
Black Box Warnings Risk to children exposed in utero

UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556

This site is intended for the staff of Iredell Health System. While others may view accessible pages, Iredell Health System makes no warranty, express or implied, as to the use of this information outside of Iredell Health System. The content of this policy and procedure document serves as guidance to the delivery of quality patient care. Care providers are expected to exercise critical thinking and situational awareness skills, and in specific situations to take such action as is necessary for the delivery of quality patient care.