Chemo rounding - may round chemo DOWN to nearest vial if dose within ≤ 5% of ordered dose. Chemo doses will not be rounded up. (Approved 12/18)
High Alert Drug: Chemotherapeutic Agents - Parenteral
• Stored separately in pharmacy. • Pharmacist reviews literature in order to to verify calculations and dose prescribed. • Two pharmacists independently verify preparation. • No telephone orders. Pre-printed order sheet available. • Chemo is administered by specially trained RNs. • 2 RNs independently verify pump settings and drug on continuous infusions prior to administration. • IV sites are assessed every 2 hours. • Drugs are transported in plastic bags/designated transport containers labeled with sticker indicating CHEMOTHERAPY DRUG.
Per policy, these hazardous drugs have special waste requirements.
Generic (Brand)
Waste Requirements
triptorelin (Trelstar, Triptodur)
If > 3% by weight of drug remains ⇒ BLACK BUCKET Trace amounts/uncontaminated PPE ⇒ YELLOW BUCKET
USP <800> Hazardous Drugs
Per Policy, these drugs have special handling requirements (any drug with an "AOR" is exempt from these requirements under normal circumstances).
generic (Brand) Route
Relative Risk Level
AOR?
NIOSH 2024 Table
MSHI?↑
Warnings
triptorelin (Trelstar, Triptodur) IM
Low
N/A
2B↑
NIOSH Supplemental information (2016): N/A FDA Pregancy Category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits;
Last updated: May. 29, 2025
Hazard.Drug Handling(USP 800) USP<800> Hazardous Drug
Chemo doses will not be rounded up. (Approved 12/18)
• Pharmacist reviews literature in order to to verify calculations and dose prescribed.
• Two pharmacists independently verify preparation.
• No telephone orders. Pre-printed order sheet available.
• Chemo is administered by specially trained RNs.
• 2 RNs independently verify pump settings and drug on continuous infusions prior to administration.
• IV sites are assessed every 2 hours.
• Drugs are transported in plastic bags/designated transport containers labeled with sticker indicating CHEMOTHERAPY DRUG.
Trace amounts/uncontaminated PPE ⇒ YELLOW BUCKET