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Approved Formulary
Search results for:
triamterene
triamterene
- Restricted Medications Non-Formulary / Not-stocked
Brand names: Dyrenium
No brands, forms, or strengths have been added for this generic.
Medication comments:
| 2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults. | |
|---|---|
| Medication: | triamterene (Dyrenium) |
| Criteria 3: Potentially inappropriate medications: drugs to be used with caution in older adults. (Table 4) | |
| Drug(s) | diuretics |
| Rationale | May exacerbate or cause SIADH or hyponatremia; monitor sodium levels closely when starting or changing dosages in older adults. |
| Recommendation | Use with caution |
| Quality of evidence: Moderate, Strength of Recommendation: Strong | |
| Criteria 4: Potentially clinically important drug-drug interactions that should be avoided in older adults. (Table 5) | |
| Interacting drug(s) or class(es) | potassium-sparing diuretics ⇄ RAS inhibitors (ACEIs, ARBs, ARNIs, aliskiren) |
| Risk Rationale | Increased risk of hyperkalemia. |
| Recommendation | Avoid routinely using 2 or more RAS inhibitors, or a RAS inhibitor and potassium-sparing diuretic, concurrently in those with chronic kidney disease Stage 3a or higher. |
| Quality of evidence: Moderate, Strength of Recommendation: Strong | |
| Criteria 5: medications that should be avoided or have their dosage reduced with varying levels of kidney function in older adults. (Table 6) | |
| CrCl (mL/min) at which action is required | <30 |
| Rationale | Hyperkalemia and hyponatremia |
| Recommendation | Avoid |
| Quality of evidence: Moderate, Strength of Recommendation: Strong | |
Last updated: Sep. 22, 2025