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sodium polystyrene sulfonate

sodium polystyrene sulfonate
Brand names: Kayexalate, SPS
Form Strength
SUSPENSION, ORAL 15 g/60 mL


Medication comments:
Pediatric Pharmacy Association 2025 KIDs List of Key Potentially Inappropriate Drugs in Pediatrics 
Medication: sodium polystyrene sulfonate (SPS)
Key Potentially Inappropriate Drugs in Pediatrics (KIDs) List: Second Edition (Table 1)
Drug sodium polystyrene sulfonate
Risk/Rationale Colonic perforation
Recommendation Caution in patients weighing less than 1,500 g
 Quality of evidence: Low, Strength of Recommendation: Weak

Last updated: Sep. 25, 2025



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