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pioglitazone

pioglitazone
Brand names: Actos
Form Strength
TABLET, ORAL 15 mg
Display Thiazolidinediones Class: 682028
Medication comments:
2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults.
Medication: pioglitazone (Actos)
Criteria 2: Potentially inappropriate medication use in older adults due to drug–disease or drug–syndrome interactions that may exacerbate the disease or syndrome. (Table 3)
Drug(s) ⇆ disease or syndrome thiazolidinediones ⇄ Heart failure
Rationale Potential to promote fluid retention and/or exacerbate heart failure.
Recommendation Use with caution in patients with heart failure who are asymptomatic; avoid in patients with symptomatic heart failure.
 Quality of evidence: High, Strength of Recommendation: Strong
Last updated: Sep. 19, 2025
UpToDate Lexidrug

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