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phenytoin IV

phenytoin IV
  • Restricted Medications IV Unit restrictions
Brand names: Dilantin, Dilantin IV
Form Strength
SOLUTION, INJECTABLE 50 mg/mL
Display Hydantoins Class: 281212
Medication comments:

Per policy, these medications require cardiac and/or special monitoring.
(KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
generic (Brand) / Notes                
phenytoin (Dilantin)
IV Push,IV infusion		 Y Y Y N N N N N
Per policy, these hazardous drugs have special waste requirements. 
Generic (Brand) Waste Requirements
phenytoin (Dilantin) Injection ⇒  BLACK BUCKET 
Medications Requiring Filters   
Medication Preparation Filter Administration Filter
phenytoin sodium (Dilantin) Not required. Use a 0.22 to 0.55 micron inline filter.IMH: For IV infusions, use a 0.22 micron in-line filter.
USP <800> Hazardous Drug Assessment of Risk (AOR)
Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances.
The following outlines must be followed.
generic (Brand) Route [Packaging: Manufacturer ⇒ Dispense] NIOSH Group
phenytoin (Dilantin) IV [n/a] Non - Antineoplastic
Pharmacy:
Receiving /
Storage /
Preparation

Exposure Risk:
low
 • Handling/preparation PPE Requirements: Single CX glove,  gown , and  CSTD 
• Receiving from Distributor: Standard
• Pharmacy Storage Area: IV  CSTD  Area
• Packaging/Reconstitution Location: n/a
• Compounding (Non-Sterile/Sterile) Location: Ideal: Positive pressure room
Required: Med Prep Area with Immediate Use Preparation standards
• Omnicell Load: No
Transport • Transport (dose is placed inside a plastic sealable bag): Double bag, single  CX gloves 
Nursing:
Storage /
Admin.

Exposure Risk:
medium
 • Handling/administration PPE Requirements: Single CX glove,  gown , use of  CSTD 
• Storage of Finished dose in Nursing Area/Procedural Area: Picked up from Pharmacy
• Signage on Patient Door Required: Yes
• Manipulation of Dosage Form: n/a
• Special Manipulation for Administration: n/a
Disposal /
Spills		 • Disposal of Drug Waste: Full-  black bin , trace-  yellow bin 
• Disposol of Used PPE:  yellow bin 
• Spill management: Manage like antineoplastic agents
NIOSH Supplemental Information: IARC Group 1 carcinogen; NTP
Reason for exemption of USP<800> Containment Requirements: Preg Category D. No NIOSH requirements but is highest Group for carcinogen to humans; likely only by systemic absorption. For skin contact, remove contaminated clothing, flush area with large amounts of water and soap.
Adult Extravasation Management
Generic (Brand) Vesicant / irritant Local Care
Comments / Treatment links
 phenytoin (Dilantin, Phenytek) Vesicant Warm compress
Last updated: Apr. 4, 2024
Lexicomp Online Search

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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