High Alert Drug: Chemotherapeutic Agents - Parenteral
• Stored separately in pharmacy. • Pharmacist reviews literature in order to to verify calculations and dose prescribed. • Two pharmacists independently verify preparation. • No telephone orders. Pre-printed order sheet available. • Chemo is administered by specially trained RNs. • 2 RNs independently verify pump settings and drug on continuous infusions prior to administration. • IV sites are assessed every 2 hours. • Drugs are transported in plastic bags/designated transport containers labeled with sticker indicating CHEMOTHERAPY DRUG.
Per policy, these hazardous drugs have special waste requirements.
Generic (Brand)
Waste Requirements
mitoMYcin ophthalmic (Mitosol)
If > 3% by weight of drug remains ⇒ BLACK BUCKET Trace amounts/uncontaminated PPE ⇒ YELLOW BUCKET
USP <800> Hazardous Drug Assessment of Risk (AOR)
Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances. The following outlines must be followed.
• Pharmacist reviews literature in order to to verify calculations and dose prescribed.
• Two pharmacists independently verify preparation.
• No telephone orders. Pre-printed order sheet available.
• Chemo is administered by specially trained RNs.
• 2 RNs independently verify pump settings and drug on continuous infusions prior to administration.
• IV sites are assessed every 2 hours.
• Drugs are transported in plastic bags/designated transport containers labeled with sticker indicating CHEMOTHERAPY DRUG.
Trace amounts/uncontaminated PPE ⇒ YELLOW BUCKET
The following outlines must be followed.
[Packaging: Manufacturer ⇒ Dispense]
[UD ⇒ UD]
NIOSH Table 1A↑
Receiving / Storage / Preparation
Single CX gloves
Storage / Administration
Trace- yellow bin