Reserve Injection for Ectopic Pregnancy during SHORTAGE
Chemo rounding - may round chemo DOWN to nearest vial if dose within ≤ 5% of ordered dose. Chemo doses will not be rounded up. (Approved 12/18)
High Alert Drug: Chemotherapeutic Agents - Parenteral
• Stored separately in pharmacy. • Pharmacist reviews literature in order to to verify calculations and dose prescribed. • Two pharmacists independently verify preparation. • No telephone orders. Pre-printed order sheet available. • Chemo is administered by specially trained RNs. • 2 RNs independently verify pump settings and drug on continuous infusions prior to administration. • IV sites are assessed every 2 hours. • Drugs are transported in plastic bags/designated transport containers labeled with sticker indicating CHEMOTHERAPY DRUG.
Per policy, these hazardous drugs have special waste requirements.
Generic (Brand)
Waste Requirements
methotrexate (Otrexup, Rasuvo)
If > 3% by weight of drug remains ⇒ BLACK BUCKET Trace amounts/uncontaminated PPE ⇒ YELLOW BUCKET
USP <800> Hazardous Drug Assessment of Risk (AOR)
Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances. The following outlines must be followed.
• Handling/preparation PPE Requirements: Single CX glove, gown , and CSTD (as dosage form allows)
• Receiving from Distributor: Designated area/ CX gloves
• Pharmacy Storage Area: Hazardous, Chemo zip locking bag
• Packaging/Reconstitution Location: n/a
• Compounding (Non-Sterile/Sterile) Location: Required: Med Prep Area with Immediate Use Preparation standards
• Omnicell Load: No
Transport
• Transport (dose is placed inside a plastic sealable bag): Double bag Single CX gloves
Nursing: Storage / Admin.
Exposure Risk: moderate
• Handling/administration PPE Requirements: Double CX glove, gown
• Storage of Finished dose in Nursing Area/Procedural Area: Picked up from Pharmacy
• Signage on Patient Door Required: Yes
• Manipulation of Dosage Form: 1 vial per syringe - label accordingly
• Special Manipulation for Administration: n/a
Disposal / Spills
• Disposal of Drug Waste: Full- black bin Trace- yellow bin
• Disposol of Used PPE: Yellow bin
• Spill management: Wear CX gloves ; items used to clean up spill should be placed in a sealed bag and put in yellow bin
Reason for exemption of USP<800> Containment Requirements: The act of drawing up an IM dose of methotrexate and giving it immediately is considered administration.
Chemo doses will not be rounded up. (Approved 12/18)
• Pharmacist reviews literature in order to to verify calculations and dose prescribed.
• Two pharmacists independently verify preparation.
• No telephone orders. Pre-printed order sheet available.
• Chemo is administered by specially trained RNs.
• 2 RNs independently verify pump settings and drug on continuous infusions prior to administration.
• IV sites are assessed every 2 hours.
• Drugs are transported in plastic bags/designated transport containers labeled with sticker indicating CHEMOTHERAPY DRUG.
Trace amounts/uncontaminated PPE ⇒ YELLOW BUCKET
The following outlines must be followed.
Receiving /
Storage /
Preparation
moderate
Single CX gloves
Storage /
Admin.
moderate
Spills
Trace- yellow bin
items used to clean up spill should be placed in a sealed bag and put in yellow bin