• Stored separately in pharmacy. • Drugs are transported in plastic bags/designated transport containers labeled with sticker indicating CHEMOTHERAPY DRUG.
Per policy, these hazardous drugs have special waste requirements.
Generic (Brand)
Waste Requirements
megestrol (Megace)
If > 3% by weight of drug remains ⇒ BLACK BUCKET Trace amounts/uncontaminated PPE ⇒ YELLOW BUCKET
USP <800> Hazardous Drug Assessment of Risk (AOR)
Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances. The following outlines must be followed.
• Receiving from Distributor: Designated area/ CX gloves
• Pharmacy Storage Area: Hazardous
• Packaging/Reconstitution Location: n/a
• Compounding (Non-Sterile/Sterile) Location: n/a
• Omnicell Load: Yes
Transport
• Transport (dose is placed inside a plastic sealable bag): Standard
Nursing: Storage / Administration
Exposure Risk: low
• Handling/administration PPE Requirements: via Mouth- Single pair of CX approved gloves via Tube- double CX gloves and gown Wash hands after handling
• Storage of Finished dose in Nursing Area/Procedural Area: Patient Med Drawer Omnicell
• Signage on Patient Door Required: Yes
• Manipulation of Dosage Form: Tablet crushed via RxCrush. Soln to be drawn up by nursing at bedside
• Special Manipulation for Administration: n/a
Disposal / Spills
• Disposal of Drug Waste: Full- black bin Trace- yellow bin
• Disposol of Used PPE: yellow bin
• Spill management: n/a
NIOSH Supplemental Information: Breastfeeding should be discontinued if megestrol is required. Women at risk of pregnancy should avoid exposure.
Reason for exemption of USP<800> Containment Requirements: Purchased in final dosage form; packaged as unit dose. Does not require additional manipulation for dispensing.
Last updated: May. 22, 2025
Hazard.Drug Handling(USP 800) USP<800> Hazardous Drug / Assessment of Risk
• Drugs are transported in plastic bags/designated transport containers labeled with sticker indicating CHEMOTHERAPY DRUG.
Trace amounts/uncontaminated PPE ⇒ YELLOW BUCKET
The following outlines must be followed.
[Packaging: Manufacturer ⇒ Dispense]
[UD ⇒ UD]
40 mg soln cup
NIOSH Table 2↑
Receiving / Storage / Preparation
Storage / Administration
via Tube- double CX gloves and gown
Wash hands after handling
Omnicell
Soln to be drawn up by nursing at bedside
Trace- yellow bin