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fosphenytoin

fosphenytoin

Brand names: Cerebyx

Form	Strength
SOLUTION, INJECTABLE	100 mg PE/2 mL

Display Hydantoins Class: 281212

Medication comments:

Refrigerator item

USP <800> Hazardous Drug Assessment of Risk (AOR)
Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances. The following outlines must be followed.
generic (Brand) Route [Packaging: Manufacturer ⇒ Dispense]	Activities
fosphenytoin (Cerebyx) IV [n/a]	100 mg injection, 500 mg injection	Stock @ IDBH? N NIOSH Table 2^↑
Pharmacy: Receiving / Storage / Preparation Exposure Risk: low	• Handling/preparation PPE Requirements: Single CX glove, gown
	• Receiving from Distributor: Standard
	• Pharmacy Storage Area: IV Area (fridge)
	• Packaging/Reconstitution Location: n/a
	• Compounding (Non-Sterile/Sterile) Location: Positive pressure room
	• Omnicell Load: No
Transport	• Transport (dose is placed inside a plastic sealable bag): Standard
Nursing: Storage / Administration Exposure Risk: moderate	• Handling/administration PPE Requirements: Single CX glove, gown
	• Storage of Finished dose in Nursing Area/Procedural Area: Patient Med Drawer
	• Signage on Patient Door Required: No
	• Manipulation of Dosage Form: n/a
	• Special Manipulation for Administration: n/a
Disposal / Spills	• Disposal of Drug Waste: Full- black bin Trace- yellow bin
	• Disposol of Used PPE: trash bin (inside plastic bag)
	• Spill management: Manage like antineoplastic agents
NIOSH Supplemental Information: IARC Group 1 carcinogen; NTP
Reason for exemption of USP<800> Containment Requirements: Preg Category D. No NIOSH requirements but is highest Group for carcinogen to humans; likely only by systemic absorption. For skin contact, remove contaminated clothing, flush area with large amounts of water and soap. Per MSDS, "possible carcinogen"

Last updated: May. 22, 2025

Hazard.Drug Handling(USP 800) USP<800> Hazardous Drug
Black Box Warnings Cardiovascular risk with rapid infusion

UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556

This site is intended for the staff of Iredell Health System. While others may view accessible pages, Iredell Health System makes no warranty, express or implied, as to the use of this information outside of Iredell Health System. The content of this policy and procedure document serves as guidance to the delivery of quality patient care. Care providers are expected to exercise critical thinking and situational awareness skills, and in specific situations to take such action as is necessary for the delivery of quality patient care.