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fentaNYL

fentaNYL
  • Restricted Medications Unit restrictions
Brand names: Actiq, Duragesic, fentaNYL citrate, Sublimaze
Form Strength
FILM, EXTENDED RELEASE, TRANSDERMAL 12 mcg/hr; 25 mcg/hr; 50 mcg/hr; 75 mcg/hr; 100 mcg/hr
LOZENGE, ORAL TRANSMUCOSAL 400 mcg; 600 mcg; 800 mcg; 1200 mcg; 1600 mcg
POWDER, COMPOUNDING -
SOLUTION, INJECTABLE 50 mcg/mL
Display Opioid Agonists Class: 280808
High Alert Drug : Policy
Medication comments:

fentaNYL should generally not be interrupted during procedures unless there is a specific physician order.
High Alert Drug: Epidural
 • Alert sticker placed on both sides of all bags of epidural infusions at the time of dispensing and on epidural lines
 • Special monitoring - flow sheet, EMR documentation, order sets
 • Guidelines for timing of anticoagulation
High Alert Drug: IV Narcotics/opiates used in PCA’s
 • Standardized concentrations.
 • Electronic order set.
 • Special monitoring required - flow sheet.
 • Two RNs independently verify pump settings and drug prior to administration.
Per policy, these medications require cardiac and/or special monitoring.
(KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
generic (Brand) / Notes                
fentaNYL (Sublimaze)
Epidural Key: management only		 Y Y Y Y Y N Y N
fentaNYL (Sublimaze)
IV Push, IV Infusion for pain management		 Y PCA only PCA only PCA only Y
(IV Push only w/Anesthesia staff)		 N N N
fentaNYL (Sublimaze)
IV Push sedation / analgesia by non-anesthesia personnel Key: designated staff		 Y N N N N N N N
fentanyl (Sublimaze)
PCA for End of Life Care		 Y N 1N only 1N only N N N N
Iredell Memorial Hospital ICU Adult Infusion Guidelines  
The following orders are intended to provide a specific, safe, and effective means of initiating and titrating medications for critically ill patients. Physicians may modify doses and/or parameters as necessary pending patients' status.For all medications listed below, the responsible LIP is to be notified if unable to titrate or the maximum dose is reached andgoals of therapy are not met.
Drug Name Onset Preparation Compatible fluids
fentaNYL (Sublimaze) seconds 1000 mcg/100 ml NS or D5W
Starting Dose for ICU Sedation Titration Guidelines (for increasing and decreasing doses) with Maximum dose
Begin infusion at 25 mcg/hr. titrate by 25 mcg/hr every 15 min to -2 RASS sedation score. Max dose = 300 mcg/hr.
Drug Name Onset Preparation Compatible fluids
fentaNYL (Sublimaze)
ED ONLY		 seconds 1000 mcg/100 ml NS or D5W
Starting Dose for ICU Sedation Titration Guidelines (for increasing and decreasing doses) with Maximum dose
Begin infusion at 50 mcg/hr. titrate by 25 mcg/hr every 15 min to -2 RASS sedation score. Max dose = 300mcg/hr.
Last updated: Apr. 17, 2024
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Clinical Coordinator - Laura Rollings, PharmD: ext 4597
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Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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