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ertugliflozin-metFORMIN

ertugliflozin-metFORMIN
  • Restricted Medications Non-Formulary
Brand names: Segluromet
No brands, forms, or strengths have been added for this generic.
Display Biguanides, Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors Class: 682004, 682018
Medication comments:

Per policy, orders for these non-formulary agents will be changed to formulary equivalents.
Non-Formulary Agent Formulary Equivalent
ertugliflozin-metFORMIN (Segluromet) Initiate Adult Insulin Order Set, selecting low dose AdmeLOG sliding scale insulin (unless otherwise specified) plus metFORMIN at same dose and frequency. 
2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults.
Medication: ertuglifozin (Steglatro)
Criteria 3: Potentially inappropriate medications: drugs to be used with caution in older adults. (Table 4)
Drug(s) sodium-glucose cotransporter-2 (SGLT2) inhibitors
Rationale Older adults may be at increased risk of urogenital infections, particularly women in the first month of treatment. An increased risk of euglycemic diabetic ketoacidosis has also been seen in older adults.
Recommendation Use with caution.
Monitor patients for urogenital infections and ketoacidosis.
 Quality of evidence: Moderate, Strength of Recommendation: Weak
Last updated: Sep. 19, 2025
UpToDate Lexidrug

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