Recommendations Update July 8, 2016: CDC continues to work with FDA, health departments and multiple healthcare facilities to investigate a multi-state outbreak of infections caused by Burkholderia cepacia complex (also known as “B. cepacia complex”). At this time, CDC continues to recommend that clinicians not use any liquid docusate product as a stool softener or for any other medical purpose. This recommendation is now expanded to all patient populations. If an oral liquid docusate stool softener is medically necessary, alternative medicines should be used.
Hierarchy in guiding laxative use
1. Docusate
2. Miralax if docusate ineffective
3. Dulcolax PO if Miralax ineffective; Dulcolax PR if patient unable to tolerate PO
4. Milk of magnesia if Dulcolax ineffective
5. Mag citrate if Milk of Magnesia ineffective
6. Fleets Enema if Mag citrate ineffective
Per policy, orders for these non-formulary agents will be changed to formulary equivalents.
Non-Formulary Agent
Formulary Equivalent
docusate (Colace) 50 mg
docusate (Colace) 100 mg
docusate (Surfak)
docusate (Colace) 100 mg
Per policy, these hazardous drugs have special waste requirements.
Recommendations Update July 8, 2016: CDC continues to work with FDA, health departments and multiple healthcare facilities to investigate a multi-state outbreak of infections caused by Burkholderia cepacia complex (also known as “B. cepacia complex”). At this time, CDC continues to recommend that clinicians not use any liquid docusate product as a stool softener or for any other medical purpose. This recommendation is now expanded to all patient populations. If an oral liquid docusate stool softener is medically necessary, alternative medicines should be used.