dextromethorphan-quiNIDine
| 2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults. | |
|---|---|
| Medication: | dextromethorphan-quiNIDine (Nuedexta) |
| Criteria 2: Potentially inappropriate medication use in older adults due to drug–disease or drug–syndrome interactions that may exacerbate the disease or syndrome. (Table 3) | |
| Drug(s) ⇆ disease or syndrome | dextromethorphan-quiNIDine ⇄ Heart failure |
| Rationale | Concerns about QT prolongation. |
| Recommendation | Avoid |
| Quality of evidence: Low, Strength of Recommendation: Strong | |
| Criteria 3: Potentially inappropriate medications: drugs to be used with caution in older adults. (Table 4) | |
| Drug(s) | dextromethorphan-quiNIDine |
| Rationale | Limited efficacy in patients with behavioral symptoms of dementia (does not apply to the treatment of pseudobulbar affect). May increase the risk of falls and concerns with clinically significant drug interactions and with use in those with heart failure (see Table 3). |
| Recommendation | Use with caution |
| Quality of evidence: Moderate, Strength of Recommendation: Strong | |