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dextromethorphan-quiNIDine

dextromethorphan-quiNIDine
  • Restricted Medications Non-Formulary / Not-stocked
Brand names: Nuedexta
No brands, forms, or strengths have been added for this generic.

Medication comments:
2023 American Geriatrics Society Beers Criteria® for potentially inappropriate medication use in older adults.
Medication: dextromethorphan-quiNIDine (Nuedexta)
Criteria 2: Potentially inappropriate medication use in older adults due to drug–disease or drug–syndrome interactions that may exacerbate the disease or syndrome. (Table 3)
Drug(s) ⇆ disease or syndrome dextromethorphan-quiNIDine ⇄ Heart failure
Rationale Concerns about QT prolongation.
Recommendation Avoid
 Quality of evidence: Low, Strength of Recommendation: Strong
 
Criteria 3: Potentially inappropriate medications: drugs to be used with caution in older adults. (Table 4)
Drug(s) dextromethorphan-quiNIDine
Rationale Limited efficacy in patients with behavioral symptoms of dementia (does not apply to the treatment of pseudobulbar affect). May increase the risk of falls and concerns with clinically significant drug interactions and with use in those with heart failure (see Table 3).
Recommendation Use with caution
 Quality of evidence: Moderate, Strength of Recommendation: Strong

Last updated: Sep. 24, 2025



Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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