dexrazoxane
Form | Strength |
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POWDER FOR INJECTION, INTRAVENOUS | 500 mg |
Per policy, these hazardous drugs have special waste requirements. | |
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Generic (Brand) | Waste Requirements |
dexrazoxane (Totect, Zinecard) | Hazardous Waste ⇒ BLACK BUCKET |
USP <800> Hazardous Drugs | ||||||
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Per Policy, these drugs have special handling requirements (any drug with an "AOR" is exempt from these requirements under normal circumstances). | ||||||
generic (Brand) Route | Relative Risk Level | AOR? | NIOSH 2024 Table | MSHI?↑ | Warnings | |
dexrazoxane (Totect, Zinecard) IV | High | N/A | 1↑ | Yes | ||
NIOSH Supplemental information (2016): secondary malignancies observed in patients treated long term with Razoxane (a racemic mixture containing dexrazoxane); genotoxic in vitro and in vivo; in laboratory studies, testicular atrophy observed at or below the human dose FDA Pregancy Category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks; |