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conjugated estrogens IV

conjugated estrogens IV

Brand names: Premarin Intravenous

Form	Strength
POWDER FOR INJECTION, INJECTABLE	25 mg

Display Estrogens, Bone Resorption Inhibitors Class: 681604, 922400

Medication comments:

Refrigerator item

USP <800> Hazardous Drug Assessment of Risk (AOR)
Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances. The following outlines must be followed.
generic (Brand) Route [Packaging: Manufacturer ⇒ Dispense]	Activities
estrogens, conjugated (Premarin) IV [n/a]		Stock @ IDBH? N NIOSH Table 1^A↑
Pharmacy: Receiving / Storage / Preparation Exposure Risk: low	• Handling/preparation PPE Requirements: Single CX glove, gown
	• Receiving from Distributor: Standard
	• Pharmacy Storage Area: IV (fridge)
	• Packaging/Reconstitution Location: n/a
	• Compounding (Non-Sterile/Sterile) Location: Positive pressure room
	• Omnicell Load: No
Transport	• Transport (dose is placed inside a plastic sealable bag): Standard
Nursing: Storage / Administration Exposure Risk: low	• Handling/administration PPE Requirements: Single pair of CX approved gloves Wash hands after handling
	• Storage of Finished dose in Nursing Area/Procedural Area: Patient Med Drawer
	• Signage on Patient Door Required: No
	• Manipulation of Dosage Form: n/a
	• Special Manipulation for Administration: n/a
Disposal / Spills	• Disposal of Drug Waste: Full- black bin Trace/packaging- yellow bin
	• Disposol of Used PPE: trash bin (inside plastic bag)
	• Spill management: Wear CX gloves items used to clean up spill should be placed in a sealed bag and put in blue bin
NIOSH Supplemental Information: BBW for malignant neoplasms; increased risk of endometrial, ovarian and breast cancer; in laboratory studies, increased frequency of carcinomas of breast, uterus, cervix, vagina, testis, and liver; present in breast milk. Listed by NTP and IARC. Not listed by OSHA. Take up mechanically and collect in suitable container for disposal. Clean contaminated surface thoroughly.
Reason for exemption of USP<800> Containment Requirements: Pregnancy Category X. Risks are related to systemic absorption.

Last updated: May. 22, 2025

Hazard.Drug Handling(USP 800) USP<800> Hazardous Drug / Assessment of Risk
Black Box Warnings Endometrial cancer; cardiovascular; dementia risk

UpToDate Lexidrug

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556

This site is intended for the staff of Iredell Health System. While others may view accessible pages, Iredell Health System makes no warranty, express or implied, as to the use of this information outside of Iredell Health System. The content of this policy and procedure document serves as guidance to the delivery of quality patient care. Care providers are expected to exercise critical thinking and situational awareness skills, and in specific situations to take such action as is necessary for the delivery of quality patient care.