FormWeb • conjugated estrogens IV

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conjugated estrogens IV

conjugated estrogens IV

Brand names: Premarin Intravenous

Form	Strength
POWDER FOR INJECTION, INJECTABLE	25 mg

Display Estrogens Class: 681604

Medication comments:

Refrigerator item

USP <800> Hazardous Drug Assessment of Risk (AOR)
Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances. The following outlines must be followed.
generic (Brand) Route [Packaging: Manufacturer ⇒ Dispense]		NIOSH Group
estrogens, conjugated (Premarin) IV [n/a]		Non - Antineoplastic
Pharmacy: Receiving / Storage / Preparation Exposure Risk: low	• Handling/preparation PPE Requirements: Single CX glove, gown and CSTD
	• Receiving from Distributor: Standard
	• Pharmacy Storage Area: Refrigerator
	• Packaging/Reconstitution Location: n/a
	• Compounding (Non-Sterile/Sterile) Location: Ideal: Positive pressure room Required: Med Prep Area with Immediate Use Preparation standards
	• Omnicell Load: No
Transport	• Transport (dose is placed inside a plastic sealable bag): Double Bag; single CX gloves
Nursing: Storage / Admin. Exposure Risk: low	• Handling/administration PPE Requirements: Double CX gloves and gown ; Use of CSTD
	• Storage of Finished dose in Nursing Area/Procedural Area: Patient Med Drawer
	• Signage on Patient Door Required: Yes
	• Manipulation of Dosage Form: n/a
	• Special Manipulation for Administration: n/a
Disposal / Spills	• Disposal of Drug Waste: Full- black bin , trace/packaging- yellow bin
	• Disposol of Used PPE: yellow bin
	• Spill management: Wear CX gloves , items used to clean up spill should be placed in a sealed bag and put in blue bin
NIOSH Supplemental Information: BBW for malignant neoplasms; increased risk of endometrial, ovarian and breast cancer; in laboratory studies, increased frequency of carcinomas of breast, uterus, cervix, vagina, testis, and liver; present in breast milk
Reason for exemption of USP<800> Containment Requirements: NIOSH recommends PPE + CSTD for preparation. PPE + CSTD required for administration. Pregnancy Category X. Risks are related to systemic absorption.

Last updated: Apr. 4, 2024

Hazard.Drug Handling(USP 800) USP<800> Hazardous Drug / Assessment of Risk
Black Box Warnings Endometrial cancer; cardiovascular; dementia risk

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556

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The content of this policy and procedure document serves as guidance to the delivery of quality patient care.
Care providers are expected to exercise critical thinking and situational awareness skills,
and in specific situations to take such action as is necessary for the delivery of quality patient care.