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cidofovir

cidofovir
Brand names: Vistide
Form Strength
SOLUTION, INTRAVENOUS 75 mg/mL


Medication comments:
USP <800> Hazardous Drug Assessment of Risk (AOR)
Per policy, these drugs are exempt from USP <800> handling requirements under normal circumstances.
The following outlines must be followed.
generic (Brand) Route
[Packaging: Manufacturer ⇒ Dispense]
Activities
cidofovir (Vistide) IV
[Vial ⇒ ]
 75 mg/mL (5 mL) vial Stock @ IDBH? N
NIOSH Table 1
Pharmacy:
Receiving / Storage / Preparation


Exposure Risk: low
• Handling/preparation PPE Requirements: Single CX gloves, gown
• Receiving from Distributor: Standard
• Pharmacy Storage Area: IV Area
• Packaging/Reconstitution Location: n/a
• Compounding (Non-Sterile/Sterile) Location: Positive pressure room
• Omnicell Load: No
Transport • Transport (dose is placed inside a plastic sealable bag): Standard
Nursing:
Storage / Administration


Exposure Risk: low
• Handling/administration PPE Requirements: Single pair of CX approved gloves, gown. Wash hands after handling
• Storage of Finished dose in Nursing Area/Procedural Area: Patient Med Drawer
• Signage on Patient Door Required: No
• Manipulation of Dosage Form: n/a
• Special Manipulation for Administration: n/a
Disposal / Spills • Disposal of Drug Waste: Full-  black bin 
Trace-  yellow bin 
• Disposol of Used PPE: trash bin (inside plastic bag)
• Spill management:
NIOSH Supplemental Information: MSHI
Reason for exemption of USP<800> Containment Requirements: Pregnancy Category C. MSHI recommends following NIOSH. Also notes, if cidofovir contacts the skin, wash membranes and flush thoroughly with water. Due to the mutagenic properties of cidofovir, adequate precautions including the use of appropriate safety equipment are recommended for the preparation, administration, and disposal of VISTIDE. NIOSH presently recommends that such agents be prepared in a Class II laminar flow biological safety cabinet and that personnel preparing drugs of this class wear surgical gloves and a closed front surgical-type gown with knit cuffs. Excess VISTIDE and all other materials used in the admixture preparation and administration should be placed in a leak-proof, puncture-proof container. The recommended method of disposal is high temperature incineration. Risks are related to systemic absorption.

Last updated: May. 22, 2025



Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



This site is intended for the staff of Iredell Health System. While others may view accessible pages, Iredell Health System makes no warranty, express or implied, as to the use of this information outside of Iredell Health System. The content of this policy and procedure document serves as guidance to the delivery of quality patient care. Care providers are expected to exercise critical thinking and situational awareness skills, and in specific situations to take such action as is necessary for the delivery of quality patient care.