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cefotaxime

cefotaxime

Restricted Medications Non-Formulary

Brand names: Claforan

Form	Strength
POWDER FOR INJECTION, INJECTABLE	1 g; 2 g

Display Third Generation Cephalosporins Class: 08120612

Medication comments:

Per policy, these drugs are subject to renal dosing adjustments by pharmacy.
Generic + Route (Brand) • Indications	Usual Adult Dose Comments	Renal Dosage Adjustments
cefotaxime IV/IM (Claforan^©)	usual indication-specific dose = 2 gm q4h	CrCl > 50: No adjustment necessary CrCl > 10-50: 2 gm q6-8h CrCl ≤ 10: 2 gm q12h HD (3x weekly): 2 gm q12h PD: 2 gm q12h
cefotaxime IV/IM (Claforan^©)	usual indication-specific dose = 1-2 gm q6h	CrCl > 50: No adjustment necessary CrCl > 10-50: 1-2 gm q8h CrCl ≤ 10: 1-2 gm q12h HD (3x weekly): 1-2 gm q12h PD: 1-2 gm q12h
cefotaxime IV/IM (Claforan^©)	usual indication-specific dose = 1-2 gm q8h	CrCl > 50: No adjustment necessary CrCl > 10-50: 1-2 gm q12h CrCl ≤ 10: 1-2 gm q24h HD (3x weekly): 1-2 gm q24h PD: 1-2 gm q24h

Per policy, orders for these non-formulary agents will be changed to formulary equivalents.
Non-Formulary Agent	Formulary Equivalent
cefotaxime (Claforan) q8h or q12h (adult)	cefTRIAXone (Rocephin) q24h

Per policy, these antibiotic medications may be given IV push.
generic (Brand)	Reconstitution Amount	Reconstitution Diluent	Give over
Copy/Paste comments for PharmNet
cefotaxime (Claforan)	1 gm vial = 10 ml	Sterile Water for Injection	3-5 mins
Dilute with 10 ml Sterile Water for Injection and give over 3-5 mins.

Last updated: Apr. 17, 2024

Renal Adjustment Policy cefotaxime subject to adjustments by pharmacy.
Therapeutic Interchange Policy cefTRIAXone (Rocephin)

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556

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While others may view accessible pages, Iredell Memorial Hospital makes no warranty, express or implied,
as to the use of this information outside of Iredell Memorial Hospital.
The content of this policy and procedure document serves as guidance to the delivery of quality patient care.
Care providers are expected to exercise critical thinking and situational awareness skills,
and in specific situations to take such action as is necessary for the delivery of quality patient care.