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cefepime

cefepime

Brand names: Maxipime

Form	Strength
POWDER FOR INJECTION, INJECTABLE	1 g; 2 g

Display Fourth Generation Cephalosporins Class: 08120616

Medication comments:

Per policy, these drugs are subject to renal dosing adjustments by pharmacy.
Generic + Route (Brand) • Indications	Usual Adult Dose Comments	Renal Dosage Adjustments
cefepime IV (Maxipime^©) • Sepsis • Febrile neutropenia • Pseudomonas	2 gm q8h ONLY for severe infections	For usual recommended dose = 2 gm q8h CrCl > 60: No adjustment necessary CrCl 30-60: 2 gm q12h CrCl 11-29: 1 gm q12h or 2 gm q24h CrCl < 11 or HD: 1 gm q24h
cefepime IV/IM (Maxipime^©) • Other infections	1-2 gm q8-12h	For usual recommended dose = 2 gm q12h CrCl > 60: No adjustment necessary CrCl 30-60: 1 gm q12h CrCl 11-29: 1 gm q24h CrCl < 11 or HD: 500 mg q24h
cefepime IV/IM (Maxipime^©) • Other infections	1-2 gm q8-12h	For usual recommended dose = 1 gm q6h CrCl > 60: No adjustment necessary CrCl 30-60: 1 gm q8h CrCl 11-29: 1 gm q12h CrCl < 11 or HD: 1 gm q24h
cefepime IV/IM (Maxipime^©) • Other infections	1-2 gm q8-12h	For usual recommended dose = 1 gm q12h CrCl > 60: No adjustment necessary CrCl 30-60: 1 gm q24h CrCl 11-29: 500 mg q24h CrCl < 11 or HD: 250 mg q24h

Per policy, these antibiotic medications may be given IV push.
generic (Brand)	Reconstitution Amount	Reconstitution Diluent	Give over
Copy/Paste comments for PharmNet
cefepime (Maxipime)	1 gm vial = 10 ml	Sterile Water for Injection	3-5 mins
Dilute with 10 ml Sterile Water for Injection and give over 3-5 mins.
cefepime (Maxipime)	2 gm vial = 20 ml	Sterile Water for Injection	3-5 mins
Dilute with 20 ml Sterile Water for Injection and give over 3-5 mins.

Last updated: May. 24, 2021

Renal Adjustment Policy cefepime subject to adjustments by pharmacy.

Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556

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as to the use of this information outside of Iredell Memorial Hospital.
The content of this policy and procedure document serves as guidance to the delivery of quality patient care.
Care providers are expected to exercise critical thinking and situational awareness skills,
and in specific situations to take such action as is necessary for the delivery of quality patient care.