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DOXOrubicin liposomal

DOXOrubicin liposomal
  • Restricted Medications IV Chemotherapy
Brand names: Doxil, Lipodox, Myocet
Form Strength
DISPERSION, INTRAVENOUS 2 mg/mL
Display Antineoplastic Agents Class: 100000
High Alert Drug : Policy
Medication comments:

Chemo rounding - may round chemo DOWN to nearest vial if dose within ≤ 5% of ordered dose.
Chemo doses will not be rounded up. (Approved 12/18)
High Alert Drug: Chemotherapeutic Agents - Parenteral
 • Stored separately in pharmacy.
 • Pharmacist reviews literature in order to to verify calculations and dose prescribed.
 • Two pharmacists independently verify preparation.
 • No telephone orders. Pre-printed order sheet available.
 • Chemo is administered by specially trained RNs.
 • 2 RNs independently verify pump settings and drug on continuous infusions prior to administration.
 • IV sites are assessed every 2 hours.
 • Drugs are transported in plastic bags/designated transport containers labeled with sticker indicating CHEMOTHERAPY DRUG.
Per policy, these medications require cardiac and/or special monitoring.
(KEY: "Y" = may be given as described on chart. "N" = may NOT be given except in Rapid Response/Code Blue situations or as otherwise described in Exceptions section of Policy.
generic (Brand) / Notes                
cytotoxic agents (chemotherapy)
IV Push, IV Infusion (chemotherapy) Key: certified RN and 1N designated staff only		 Y
(CCU only)		 N N Y
(1N only)		 N N Y N
Per policy, these hazardous drugs have special waste requirements. 
Generic (Brand) Waste Requirements
DOXOrubicin liposomal (Doxil) If > 3% by weight of drug remains ⇒  BLACK BUCKET 
Trace amounts/uncontaminated PPE ⇒  YELLOW BUCKET 
USP <800> Hazardous Drugs 
Per Policy, these drugs have special handling requirements (any drug with an "AOR" is exempt from these requirements under normal circumstances).
generic (Brand) Route Risk Level AOR? Warnings
(hover over entry for details)
 DOXOrubicin liposomal (Doxil) IV High No  IARC-2A NTP-2 FDA-D
Receiving • Gloves: Single
Pharmacy:
Preparation		 • Gloves: Double
• Gown: Yes
• Ventilated Engineering controls: Yes, Class II bio-safety cabinet or compounding aseptic containment isolator
• Closed System Transfer Device: Yes
Nursing:
Administration		 • Gloves: Double
• Gown: Yes
• Eye/face protection: ---
• Closed System Transfer Device: Yes
Last updated: Jun. 12, 2024
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Pharmacy Contact Info:

Main Inpatient Pharmacy: ext 4599, 3503
Fax: 704-878-7283

Director of Pharmacy - Randi Raynor, PharmD: ext 4501
Clinical Coordinator - Laura Rollings, PharmD: ext 4597
Pharmacy Informaticist - Stephen Pringle, PharmD: ext 7645
Pharmacy Technician Supervisor - Amy Wingler, CPhT: ext 7385
Pharmacy Automation Coordinator (Omnicell) - Melissa Fulford, CPhT: ext 3556



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