Medications not yet evaluated by P&T are considered NON-FORMULARY . . . . . Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step! . . . . . Please be sure to document all clinical activities daily.
Search results for:

zoledronic acid

zoledronic acid
  • Restricted Reclast --> Restricted to Outpatient Medical.
  • Restricted Zometa --> Restricted to use by: oncology, nephrology, rheumatology, endocrinology. Hospitalists limited to treatment of hypercalcemia of malignancy using the Powerplan
  • Therapeutic Interchange Bisphosphonate Formulary
  • Therapeutic Interchange Miscellaneous Program Formulary
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Zometa SOLUTION, INTRAVENOUS 4 mg/5 mL    
Reclast SOLUTION, INTRAVENOUS 5 mg/100 mL      


Comments:

ORDERED FORMULATION

THERAPEUTIC INTERCHANGE

pamidronate (Aredia)

  • 90 mg; infuse over 2 hours.

zoledronic acid (Zometa)

  • 4 mg

Reclast medication guide


Reclast is formulary, restricted to the Outpatient Medical Department ONLY. Any order for an inpatient should be deferred to the outpatient setting.


ADULTS: 4 mg is the usual dose for zoledronic acid; The 3 mg, 3.3 mg, and 3.5 mg doses are for renal adjustments (not automatic). For HYPERCALCEMIA of MALIGNANCY use the 4 mg dose regardless of renal function

 

For HYPERCALCEMIA of MALIGNANCY, ordering through the HOSP ADULT Hypercalcemia of Malignancy Orders Powerplan is recommended. Use of the Powerplan is required for hospitalists to order zoledronic acid

 

Pamidronate is restricted to "no substitution" orders, otherwise interchange to zoledronic acid (Zometa) at a dose ratio of pamidronate 90 mg = Zoledronic acid 4 mg.


Reviewed: September 25, 2007 (Reclast) and August 27, 2013 and December 17, 2013 (Zometa interchange), October 22, 2019

 


Last updated: Sep. 18, 2024







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