Medications not yet evaluated by P&T are considered NON-FORMULARY . . . . . Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step! . . . . . Please be sure to document all clinical activities daily.
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raNITIdine

raNITIdine
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Zantac SOLUTION, INJECTABLE 25 mg/mL    
Zantac SYRUP, ORAL 15 mg/mL    
Zantac TABLET, ORAL 75 mg, 150 mg, 300 mg    


Comments:

FDA Recall (April 2020): All ranitidine (IV and Oral) products removed from the market.  Recommend and convert to famotdine as needed.

 

ORDERED FORMULATION FORMULARY INTERCHANGE

raNITIdine (Zantac)

  • 150 mg PO daily
  • 150 mg PO BID
  • 300 mg PO qhs
  • raNITIdine oral liquid (PEDS)
  • 50 mg IV q12h
  • 50 mg IV q8h
  • 50 mg IV q6h
  • 100 mg/day continuous infusion
  • 150 mg/day continuous infusion
  • 200 mg/day continuous infusion

famotidine (Pepcid)

  • 20 mg PO qhs
  • 20 mg PO BID
  • 40 mg PO qhs
  • See Peds famotidine dosing below
  • 20 mg IV daily
  • 20 mg IV q12h
  • 20 mg IV q12h
  • 20 mg/day continuous infusion
  • 40 mg/day continuous infusion
  • 40 mg/day continuous infusion
raNITIdine (Zantac)
  • 75 mg tablet BID
cimetidine (Tagamet)
  • 200 mg tablet BID

 

Pediatric dosing of famotidine:

  • < 3 months = 0.5 mg/kg Daily
  • ≥ 3 months = 0.5 mg/kg BID
  • Maximum pediatric general dose = 40 mg/day
  • If patient able to take adult tablets with tolerance and dosage, tablets will be used.

 


If H2 blocker prescribed with PPO, discontinue H2 blocker after 48 hours. Exception if GI physician -- check with physician that H2 blocker is not being used for a non-GI use prior to discontinuing.


 

Automatic IV to PO conversion per IV to oral conversion guidelines. IV to PO Conversion Guidelines

 

Updated: 3 April 2020 (FDA Removed from Market), 28 April 2020


Last updated: Apr. 29, 2020







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