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Search results for:

nitrofurantoin

nitrofurantoin
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Macrobid CAPSULE, ORAL macrocrystals-monohydrate 100 mg      
Macrodantin CAPSULE, ORAL macrocrystals 25 mg, macrocrystals 50 mg, macrocrystals 100 mg    
Furadantin SUSPENSION, ORAL 25 mg/5 mL    
VIEW MORE Urinary Anti-infectives
CLASS
083600
Comments:

Nitrofurantoin macrocrystals (Macrodantin, Furadantin) is restricted to pediatrics or situations when oral Macrobid administration is not possible (G tube administration/patients who cannot swallow capsules). Orders for Macrondantin/Furadantin in adult patients should be automatically interchanged to Macrobid.

 

ORDERED FORMULATION THERAPEUTIC INTERCHANGE

Nitrofurantoin macrocrystals (Macrodantin)

  • 25 mg
  • 50 mg
  • 100 mg

Nitrofurantoin monohydrate/macrocrystals (Macrobid)

  • 100 mg

 

For treatment of urinary tract infection, Macrobid should be used as 100 mg twice daily regardless of dose or frequency of Macrodantin ordered.

For UTI prophylaxis, Macrobid should be used as 100 mg once daily.

 

Avoid use when CrCl < 30 mL/min.  See Antimicrobial Dosing Guideline and Renal Adjustment Policy (Adult).  CrCl calculation policy available here.

 

Updated: May 2025

 

Nitrofurantoin Formulary Interchange SBAR

Last updated: Jun. 13, 2025






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