Evzio Auto-Injector is classified as non-formulary, not stocked. It should be interchanged to generic nalOXone injection.
Narcan, Kloxxado, & RiVive nasal spray are non-formulary, not stocked. For hospital setting, use intravenous, intramuscular, or nebulized nalOXone as they have a faster onset.
Pharmacists may automatically add a PRN order for nalOXone to a patient’s medication profile if the patient has opiates ordered via any route or frequency, including PRN.
To improve safety with other opiates:
Pharmacist can automatically add a PRN order for nalOXone for patients receiving the following:
Injectable opiates, PRN, scheduled or continuous
Oral opiates, PRN, or scheduled
Opiates through other routes (ex. fentaNYL patch)
The order would read as follows:
nalOXone (Narcan) 0.1 mg IV q1 min x 4 PRN RR<7, apnea, or over-sedation. Max dose of 0.4 mg
The order would be designated as, "Per P&T Policy," to indicate that the order had been added by the pharmacist.
Evzio Auto-Injector is classified as non-formulary, not stocked. It should be interchanged to generic nalOXone injection.
Narcan, Kloxxado, & RiVive nasal spray are non-formulary, not stocked. For hospital setting, use intravenous, intramuscular, or nebulized nalOXone as they have a faster onset.
Pharmacists may automatically add a PRN order for nalOXone to a patient’s medication profile if the patient has opiates ordered via any route or frequency, including PRN.
To improve safety with other opiates:
Reviewed: July 22, 2014 (Evzio), and 28 June 2016 (Nasal Spray), May 2023 (Kloxxado), December 2023 (RiVive)
Spotlight Naloxone High Dose (Kloxxado)
naloxone HCI nasal spray (RiVive)