Approved Hospital Formulary
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Approved Hospital Formulary
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ketorolac
ketorolac
- Formulary NSAID Formulary
Last updated: Jun. 12, 2024
- Black Box Warning: Duration of therapy; max dose; GI, cardiovascular, bleeding, renal risk
- Black Box Warning: Sprix: Risk of Serious Cardiovascular and Gastrointestinal Events
Sprix medication guide
Toradol medication guide
NSAID -- maybe scheduled with meals.
Ketorolac automatic stop order for oral and injectable drug if regularly scheduled doses, maximum duration of therapy is 5 days. Notify MD for ketorolac discontinuation and selection of alternative drug.
For ketorolac injection, the automatic pharmacist dosage adjustment for adults is as follows:
Route
Single Dose
Maintenance Dose
Adult
Any of the following:
· Age ≥65,
· Wt <50 kg, or
· eCrCl 30-50 mL/min#
Adult
Any of the following:
· Age ≥65,
· Wt <50 kg, or
· eCrCl 30-50 mL/min#
IM
30-60 mg*
15 mg
30 mg every 6 hours
max 120 mg/day
15 mg every 6 hours
max 60 mg/day
IV
30 mg
15 mg
30 mg every 6 hours
max 120 mg/day
15 mg every 6 hours
max 60 mg/day
Oral
10 or 20ⱡ mg
10 mg
10 mg every 4-6 hours
max 40 mg/day
10 mg every 4-6 hours
max 40 mg/day
Stop Order - 5 days for I.V., I.M., oral; should discontinue drug and communicate to nurse / physician
* 60 mg I.M. loading dose optional, 60 mg I.V. dose not recommended
ⱡ 20 mg oral only as continuation of IM or IV therapy, not for initial therapy
# for eCrCl < 30 mL/min or ESRD, recommend to physician that ketorolac be discontinued
Ketorolac dosing protocol
Pediatrics: Maximum dose of 15 mg IV/IM for inpatient orders. Any ordered dose > 15 mg may be automatically adjusted down to 15 mg by the verifying pharmacist.
The maximum duration is 5 days or 20 doses in a 30 day period. Exceptions include physician requests.
SPRIX is non-formulary, not stocked. Contact the prescriber for an alternative analgesic. If necessary, a patient may use his/her own supply.
Reviewed: April 26, 2011 (SPRIX)
Updated: November 2023 (Pediatrics - Max dose)