Intravenous epoprostenol may be administered through inhalation utilizing the approved PowerPlan.

VELETRI for IV injection is classified as formulary status, restricted to pulmonology/medical-intensivist, cardiology, rheumatology, and pediatric critical care. Stock as needed.

VELETRI for Inhalation is classified as formulary status, restricted to pulmonology/medical-intensivists, cardiothoracic surgeons, anesthesiologists, trauma surgeons, and cardiologist.

   ***Inhaled epoprostenol is dosed on ideal body weight rounded to the nearest 5 kg***

Ideal body weight calculation:

• • Females: 45.5 kg + 2.3 kg for every inch over 5 feet
  • Males: 50 kg + 2.3 kg for every inch over 5 feet

Inhaled VELETRI tip sheet, Inhaled VELETRI dosing guideline

FLOLAN is classified as non-formulary, not stocked. Flolan is automatically interchanged to VELETRI.

Veletri is available through two specialty pharmacies:

1. Accredo Health Group, Inc.
   • Phone: 1-866-Fight-PH (1-866-344-4874)
   • Fax: 1-866-254-2313
2. CVS Caremark, L.L.C
   • Phone: 1-877-242-2738
   • Fax: 1-877-943-1000

Ordering Veletri -- Enrollment form must be completed and signed by a prescriber

• Click Here to visit site
• Download the "enrollment form"
• Complete enrollment form and fax to one of the above specialty pharmacy locations

Reviewed: April 27, 2005 (FLOLAN) and 26 May 2015 (Veletri/Flolan), Jan 2021 (Intravenous epoprostenol)

Updated: November 2022 (inhalation)

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• Lippincott Advisor