Medications not yet evaluated by P&T are considered NON-FORMULARY . . . . . Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step! . . . . . Please be sure to document all clinical activities daily.
Search results for:

empagliflozin-metFORMIN

empagliflozin-metFORMIN
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Synjardy XR TABLET, EXTENDED RELEASE, ORAL 5 mg-1,000 mg, 10 mg-1,000 mg, 12.5 mg-1,000 mg, 25 mg-1,000 mg,    
Synjardy TABLET, ORAL 5 mg-500 mg, 5 mg-1,000 mg, 12.5 mg-500 mg, 12.5 mg-1,000 mg    
Comments:

Synjardy is approved for sample use in HH Endocrinology and Diabetes Clinics.

ORDERED FORMULATION

THERAPEUTIC INTERCHANGE

empagliflozin-metFORMIN (Synjardy)                  

  • 5 mg-500 mg tablet BID                      
  • 5 mg-1,000 mg tablet BID
  • 12.5 mg-500 mg tablet BID                            
  • 12.5 mg-1,000 mg tablet BID

 

empagliflozin (Jardiance) AND metFORMIN (Fortamet, Glumetza)

  • ONE 10 mg empagliflozin tablet PLUS ONE 1,000 mg metFORMIN extended release tablet once daily
  • ONE 10 mg empagliflozin tablet PLUS TWO 1,000 mg metFORMIN extended release tablets (Total: 2,000 mg) once daily
  • ONE 25 mg empagliflozin tablet PLUS ONE 1,000 mg metFORMIN extended release tablet once daily
  • ONE 25 mg empagliflozin tablet PLUS TWO 1,000 mg metFORMIN extended release tablets (Total: 2,000 mg) once daily

empagliflozin-metFORMIN (Synjardy XR)**

  • 5 mg-1000 mg tablet - TWO tablets once daily 
  • 10 mg-1,000 mg tablet - ONE tablet once daily
  • 12.5 mg-1000 mg tablet - TWO tablets once daily 
  • 25 mg-1,000 mg tablet - ONE tablet once daily

empagliflozin (Jardiance) AND metFORMIN (Fortamet, Glumetza)

  • ONE empagliflozin 10 mg tablet once daily PLUS TWO metFORMIN extended release 1,000 mg tablets (Total: 2,000 mg) once daily
  • ONE empagliflozin 10 mg tablet once daily PLUS ONE metFORMIN extended release 1,000 mg tablet once daily
  • ONE empagliflozin 25 mg tablet once daily PLUS TWO metFORMIN extended release 1,000 mg tablets (Total: 2,000 mg) once daily
  • ONE empagliflozin 25 mg tablet once daily PLUS ONE metFORMIN extended release 1,000 mg tablet once daily

**CAUTION: empagliflozin-metFORMIN (Synjardy XR) recommended dosing for the 5 mg-1000 mg XR and 12.5 mg-1000 mg XR tablets is for TWO tablets once daily, while recommended dosing for the 10 mg-1,000 mg XR and 25 mg-1,000 mg XR tablets is for ONE tablet once daily. Please be extra cautious when interchanging this medication to confirm that the interchange is appropriate (total daily dose of empagliflozin should be 10 mg or 25 mg). 

 

Synjardy medication guide

Synjardy XR medication guide

metFORMIN -- hold for 48 hours post IV contrast media per radiologist, contraindications with CHF, renal disease, hepatic disease, and age. Pharmacist may order SCr.

Synjardy -- empagliflozin/metFORMIN combination in 4 strengths, dosed bid. Interchange to separate drugs each in same daily dose utilizing empagliflozin once daily and metFORMIN ER once daily.

 

Reviewed: 17 Nov 2015 (Synjardy)

Last updated: Aug. 9, 2023






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