cefazolin
Automatic IV to PO conversion per IV to oral conversion guidelines. IV to PO Conversion Guidelines
Automatic renal adjustment per guidelines. See Antimicrobial Dosing Guideline and Renal Adjustment Policy (Adult) for more information. CrCl calculation policy available here.
Drug
Usual Dose
CrCl (mL/min)
Dose Adjustment
Cefazolin
Mild Infections (UTI)
1 g IV q 8h
10-29
<10/HD
CRRT
1 g IV q 12h
1 g IV q 24h, after HD
2 g x 1 then 1 g q 8-12h
Moderate to Severe Infections
(IE, OM, PNA)
2 g q8h
2 g q12h
1 g q24h, after HD
2 g x1 then 1 g q8h or 2 g q12h
Reviewed: 16 July 2024 (Renal adjustments)
Automatic IV to PO conversion per IV to oral conversion guidelines. IV to PO Conversion Guidelines
Automatic renal adjustment per guidelines. See Antimicrobial Dosing Guideline and Renal Adjustment Policy (Adult) for more information. CrCl calculation policy available here.
Drug
Usual Dose
CrCl (mL/min)
Dose Adjustment
Cefazolin
Mild Infections (UTI)
1 g IV q 8h
10-29
<10/HD
CRRT
1 g IV q 12h
1 g IV q 24h, after HD
2 g x 1 then 1 g q 8-12h
Moderate to Severe Infections
(IE, OM, PNA)
2 g q8h
10-29
<10/HD
CRRT
2 g q12h
1 g q24h, after HD
2 g x1 then 1 g q8h or 2 g q12h
Reviewed: 16 July 2024 (Renal adjustments)