Medications not yet evaluated by P&T are considered NON-FORMULARY. Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step!
Please be sure to document all clinical activities daily.
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canagliflozin-metFORMIN

canagliflozin-metFORMIN
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Invokamet XR TABLET, EXTENDED RELEASE, ORAL 50 mg-500 mg, 150 mg-500 mg, 50 mg-1000 mg, 150 mg-1000 mg    
Invokamet TABLET, ORAL 50 mg-1000 mg, 50 mg-500 mg, 150 mg-1000 mg, 150 mg-500 mg    
Comments:
ORDERED FORMULATION THERAPEUTIC INTERCHANGE
canagliflozin-metFORMIN (Invokamet)                              
  • 50 mg-1,000 mg tablet BID                                                                                                   
  • 50 mg-500 mg tablet BID                                                      
  • 150 mg-1,000 mg tablet BID                                                                                               
  • 150 mg-500 mg tablet BID
 canagliflozin (Invokana) AND metFORMIN (Glucophage XR)
  • ONE 100 mg canagliflozin PLUS TWO 1,000 mg metFORMIN ER tablets (Total:2,000 mg) ONCE Daily
  • ONE 100 mg canagliflozin PLUS ONE 1,000 mg metFORMIN ER tablet ONCE Daily
  • ONE 300 mg canagliflozin PLUS TWO 1,000 mg metFORMIN ER tablets (Total:2,000 mg) ONCE Daily
  • ONE 300 mg canagliflozin PLUS ONE 1,000 mg metFORMIN ER tablet ONCE Daily

canagliflozin-metFORMIN (Invokamet XR)

  • 50 mg-500 mg 2 tablets once daily                                                                              
  • 50 mg-1,000 mg 2 tablets daily                                                                                         
  • 150 mg-500 mg 2 tablets daily                                                                                 
  • 150 mg-1,000 mg 2 tablets daily

canagliflozin (Invokana) AND metFORMIN (Glucophage XR)

  • ONE 100 mg canagliflozin tablet plus TWO 500 mg metFORMIN ER tablets (Total: 1,000 mg) ONCE Daily
  • ONE 100 mg canagliflozin tablet plus FOUR 500 mg metFORMIN ER tablets (Total: 2,000 mg) ONCE Daily
  • ONE 300 mg canagliflozin tablet plus TWO 500 mg metFORMIN ER tablets (Total: 1,000 mg) ONCE Daily
  • ONE 300 mg canagliflozin tablet plus FOUR 500 mg metFORMIN ER tablets (Total: 2,000 mg) ONCE Daily

Invokamet medication guide

Invokamet XR medication guide

metFORMIN -- hold for 48 hours post IV contrast media per radiologist, contraindications with CHF, renal disease, hepatic disease, and age. Pharmacist may order SCr.

INVOKAMET is classified as non-formulary, not stocked. Dispense the individual components separately.

Reviewed: 24 February 2015 (Invokamet), and 25 April 2017 (Invokamet XR)

Last updated: Dec. 27, 2017






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