Hemophilia Blood Factor Flow Diagram

FEIBA Decision Tree

Emergent Reversal of Oral Anticoagulants

FEIBA Order Verification Guide

FEIBA Order Verification Guide - Addendum for Madison Hospital AFTER HOURS

FEIBA Guide for Nurses

FEIBA is the preferred prothrombin complex concentrate (PCC) product for emergent reversal of oral anticoagulants.

Approved FEIBA prescribers:

cardiologists, cardiovasular surgeons, emergency department physicians, hematologists, neurologists, neurosurgeons, vascular surgeons, and trauma surgeons.

FEIBA uses:

1. Control and prevention of bleeding episodes in patients with hemophilia A and B with inhibitors (FDA approved indication).
2. Emergent reversal of warfarin, direct thrombin inhibitors, or oral direct factor Xa inhibitor induced serious, life-threatening bleeding in adults.
3. For those adults on the above anticoagulants requiring emergent surgery.
4. Life-threatening bleeding unresponsive to alternative therapy.

FEIBA Diluent Volumes:

500 unit vial = 10 mL

1,000 unit vial = 20 mL

2,500 unit vial = 50 mL

Round dose to nearest vial size.

Reviewed: 28 Aug 2018 (FEIBA)

• Micromedex
• UpToDate
• Lippincott Advisor