Medications not yet evaluated by P&T are considered NON-FORMULARY. Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step!
Please be sure to document all clinical activities daily.
Search results for:

Ofirmev

acetaminophen
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Tylenol Dissolve Packs POWDER, ORAL 160 mg, 500 mg      
Ofirmev SOLUTION, INTRAVENOUS 10 mg/mL      
Feverall Infants SUPPOSITORY, RECTAL 80 mg      
Acephen SUPPOSITORY, RECTAL 120 mg, 325 mg      
Feverall SUPPOSITORY, RECTAL 650 mg      
Tylenol SUSPENSION, ORAL 160 mg/5 mL      
Mapap TABLET, CHEWABLE, ORAL 80 mg      
Tylenol 8 Hour TABLET, EXTENDED RELEASE, ORAL 650 mg      
Tylenol TABLET, ORAL 325 mg      
Tylenol Extra Strength TABLET, ORAL 500 mg      
VIEW MORE Analgesics and Antipyretics, Miscellaneous
Comments:

OFIRMEV APPROVED USES:

  • Adults: Treatment of fever in ICU or oncology patients who are not candidates for injectable ketorolac or oral/rectal acetaminophen.
  • Pediatric patients meeting the following criteria and guidelines:
    • PDA treatment AND patient is unable to tolerate PO acetaminophen
    • Post-operative spinal fusion patients
    • Fever meeting all of the following criteria:
      • Strict NPO (including no enteral feeds)
      • Nothing PR
      • Contraindication to NSAIDS -- with at least one of the following:
        • Age <6 months
        • Allergy to NSAIDS
        • GI Bleed
        • Platelet count < 150,000
        • CrCl < 30 mL/min
        • Concurrent use of other nephrotoxic medications (vanco, aminoglycosides, etc.)
        • Other reason explained
    • Pain/Analgesia meeting the following criteria (approved by HVCC, pediatric only)
      • NPO and NPR
      • At high risk for narcotic ADRs
      • Must use approved protocol

 

Ofirmev may be automatically converted to PO (1:1 dose ratio) once the patient meets approved criteria.

Norco and Percocet Interchange for Patients Receiving Scheduled Acetaminophen: Pharmacists may automatically interchange Norco (HYDROcodone/acetaminophen) to plain oxyCODONE (at same mg dose as HYDROcodone component in original order) at the same frequency and Percocet (oxyCODONE/acetaminophen) to plain oxyCODONE (at same mg dose as oxyCODONE in original order) at the same frequency in patients receiving scheduled acetaminophen when no acetaminophen free alternative is ordered.

 

 

The Acetaminophen Protocol for Non-Opioid Pain Management  was approved for pharmacists to place orders for acetaminophen 650 mg q4 hr prn mild pain (pain score 1-3) for adult patients (>17 yo) who have prn opioids ordered without a non-opioid alternative (Acetaminophen or NSAIDs) for mild pain. See linked tip sheet for additional information.

 

 

 

Tylenol Dissolve Packs: Restricted to patients undergoing bariatric surgery.

Reviewed: February 22, 2011 and December 13, 2011 and September 26, 2012 and 26 January 2016 (Ofirmev), and 27 Feb 2018 (Ofirmev), and May 2021 (Tylenol Dissolve Packs), October 2025, and Norco and Percocet to oxyCODONE Interchange January 2026

High Value Care Committee: April 2018 (Ofirmev-Pediatric-Analgesia)

Last updated: Jul. 29, 2026






This site is intended for the staff of Huntsville Hospital.
While others may view accessible pages, Huntsville Hospital makes no warranty, express or implied,
as to the use of this information outside of Huntsville Hospital.
Please note than many documents are accessible via the provided link
only when connected to the Huntsville Hospital intranet.

Copyright © 2026 Rpharmy, LLC ­ All Rights Reserved