Medications not yet evaluated by P&T are considered NON-FORMULARY . . . . . Always check 2 unique patient identifiers - NAME and DATE OF BIRTH - at every step! . . . . . Please be sure to document all clinical activities daily.
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Mesalamine

mesalamine
  • Formulary Mesalamine Product Formulary
  • Restricted sfRowasa --> Restricted to patients who have sulfite/sulfur allergy ~OR~ are intolerant to regular mesalamine enema due to sulfite content.
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Pentasa CAPSULE, EXTENDED RELEASE, ORAL 250 mg, 500 mg      
Apriso CAPSULE, EXTENDED RELEASE, ORAL 375 mg    
Delzicol DELAYED RELEASE CAPSULE, ORAL 400 mg      
Lialda DELAYED RELEASE TABLET, ORAL 1.2 g      
Asacol DELAYED RELEASE TABLET, ORAL 400 mg    
Asacol HD DELAYED RELEASE TABLET, ORAL 800 mg    
sfRowasa (sulfite free) ENEMA, RECTAL 4 g/60 mL      
Canasa SUPPOSITORY, RECTAL 1000 mg      


Comments:

ORDERED FORMULATION

THERAPEUTIC INTERCHANGE

NOTES

mesalamine (Apriso)

  • 375 mg extended release capsule oral
    • 1.5 g daily

mesalamine (Delzicol)

  • 400 mg delayed release capsule oral
    • 400 mg QID

 

Apriso 1.5 g daily interchanged to Delzicol 400 mg QID

mesalamine (Asacol)

  • 400 mg delayed release tablet oral

mesalamine (Dezicol)

  • 400 mg delayed release capsule oral
 

mesalamine (Asacol HD)

  • 800 mg delayed release tablet
    • 800 mg TID

mesalamine (Dezicol)

  • 400 mg delayed release capsule oral
    • 800 mg (2 capsules) TID

 

Apriso HD 800 mg TID interchanged to Delzicol (400 mg x 2) TID


Asacol 400 mg tablets have been discontinued. They have been replaced with Delzicol 400 mg capsules (bioequivalent).


Asacol HD is classified as non-formulary, not stocked. Interchange to Delzicol (formerly Asacol) at the same dosing regimen.


Rowasa Sulfite Free is classified as formulary, not generally stocked - to be used as a second line drug in patients with sulfite allergy or who cannot tolerate the regular mesalamine enema product.


Reviewed: April 24, 2007 (Lialda), and February 26, 2009 (Apriso), and November 17, 2009 (Asacol HD), and June 22, 2010 (Rowasa SF enema), and June 25, 2013 (Delzicol)

 


Last updated: Dec. 21, 2017
  • Formulary, Not Routinely Stocked: sfRowasa







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