FEIBA is the PREFERRED prothrombin complex concentrate (PCC) product for controlling and preventing bleeding episodes in patients with hemophilia A and B with inhibitors
FEIBA is the NON-PREFERREDPCC for emergent reversal of oral anticoagulants and life-threatening bleeding unresponsive to alternative therapy. FEIBA may be used when Kcentra is contraindicateddue to anaphylaxis/severe reaction to heparin or proteins C or S, prior HIT, or during verified supply constraints.
Interchange orders from FEIBA to fixed-dose Kcentra unless contraindicated
Approved FEIBA prescribers:
cardiologists, cardiovasular surgeons, emergency department physicians, hematologists, medical intensivists, neurologists, neurosurgeons, vascular surgeons, and trauma surgeons.
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FEIBA is the PREFERRED prothrombin complex concentrate (PCC) product for controlling and preventing bleeding episodes in patients with hemophilia A and B with inhibitors
Hemophilia Blood Factor Flow Diagram
FEIBA is the NON-PREFERRED PCC for emergent reversal of oral anticoagulants and life-threatening bleeding unresponsive to alternative therapy. FEIBA may be used when Kcentra is contraindicated due to anaphylaxis/severe reaction to heparin or proteins C or S, prior HIT, or during verified supply constraints.
Interchange orders from FEIBA to fixed-dose Kcentra unless contraindicated
Approved FEIBA prescribers:
cardiologists, cardiovasular surgeons, emergency department physicians, hematologists, medical intensivists, neurologists, neurosurgeons, vascular surgeons, and trauma surgeons.
FEIBA Diluent Volumes:
500 unit vial = 10 mL
1,000 unit vial = 20 mL
2,500 unit vial = 50 mL
Round dose to nearest vial size.
Reviewed: 28 Aug 2018 (FEIBA)
Updated: November 2025