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DAPtomycin

DAPtomycin
Drug Name Form Strength Formulary Unrestricted Formulary Restricted Non-Formulary Interchange
Cubicin POWDER FOR INJECTION, INTRAVENOUS 250 mg, 500 mg      
VIEW MORE Cyclic Lipopeptides
CLASS
08122812
Comments:

DAPtomycin is restricted to Infectious Disease specialists.

Dose Rounding: Nearest 50 mg increment for patients 18 years and over. Use total body weight in non-obese patients and adjusted body weight in obese patients (obese if TBW/IBW is ≥130% or BMI ≥30).

Recommended AdjBW equation for daptomycin: AdjBW = IBW + 0.4(TBW-IBW)

Automatic renal adjustment per guidelines. See Antimicrobial Dosing Guideline and Renal Adjustment Policy (Adult) for more information.  CrCl calculation policy available here.

Weekly CPK monitoring.

Reviewed: 26 May 2015 (Cubicin), June 2020 (Administration Time)

Last updated: Jul. 17, 2024






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