Medications Approved for Automatic Therapeutic Interchange Dosage Conversion Guidelines (Note: “Therapeutic Interchange” should be placed in the order comments
5-HT1 Receptor Agonists
Medication Ordered
Brand Name
Dosages
Frequency
Formulary Medication
Equivalent Dose
Frequency
Almotriptan
Axert
6.25 mg
Once
Sumatriptan (Imitrex)
50 mg
Once
12.5 mg
Eletriptan
Relpax
20 mg
25 mg
40 mg
50 mg
Frovatriptan
Frova
2.5 mg
Naratriptan
Amerge
1 mg
2.5 mg
Rizatriptan
Maxalt,
Maxalt MLT
5 mg
25 mg
10 mg
50 mg
Zolmitriptan, ODT
Zomig,
Zomig Rapimelt
2.5 mg
25 mg
5 mg
50 mg
Zolmitriptan Nasal Spray
2.5 mg
Sumatriptan Nasal Spray
5 mg
5 mg
20 mg
Atriptan/Naproxen
Treximet
85 mg/500 mg
Sumatriptan + Naproxen (individual components)
Sumatriptan 50mg + Naproxen 500mg
Rizatriptan approved for use in patients who have failed sumatriptan
Last updated: Jun. 12, 2022
Therapeutic Interchange: T.I.
Restricted: rizatroptan (Maxalt) is restricted to patients intolerant to sumatriptan
Medications Approved for Automatic Therapeutic Interchange Dosage Conversion Guidelines
(Note: “Therapeutic Interchange” should be placed in the order comments
5-HT1 Receptor Agonists
Almotriptan
Maxalt,
Maxalt MLT
Zomig,
Zomig Rapimelt
Rizatriptan approved for use in patients who have failed sumatriptan