Medications Approved for Automatic Therapeutic Interchange Dosage Conversion Guidelines (Note: “Therapeutic Interchange” should be placed in the order comments)
H2 Antagonists
Medication Ordered
Brand Name
Available Dosages
Frequency
Formulary Medication
Equivalent Dose
Frequency
Ranitidine
Zantac
75 mg
75 mg BID
Famotidine
10 mg
BID
150 mg
150 mg BID
20 mg
BID
300 mg
Daily
40 mg
Daily
Cimetidine
Tagamet
300 mg
Q4-6hours
20 mg
BID
400 mg
BID
20 mg
BID
600-800 mg
Daily
40 mg
Daily
Nizatidine
Axid
75 mg
BID
10 mg
BID
150 mg
BID
20 mg
BID
300 mg
Daily
40 mg
Daily
Note: If the dosing falls outside of the above dosing, contact the MD to clarify conversion.
* Famotidine dosage will be adjusted to 20 mg q24h when CrCl < 50 ml/min and no active GI bleeding
** IV Cimetidine will be available for acute allergic reactions if desired
Drug Name
Common Side Effects
Ranitidine
headache, dizziness
GI: constipation, diarrhea
unpleasant taste in your mouth
Last updated: Dec. 9, 2021
Therapeutic Interchange: T.I.
Restricted: raNITIdine (Zantac) is restricted to pediatric patients
Medications Approved for Automatic Therapeutic Interchange Dosage Conversion Guidelines
(Note: “Therapeutic Interchange” should be placed in the order comments)
H2 Antagonists
Medication
Ordered
Brand Name
Available Dosages
Frequency
Formulary Medication
Equivalent
Dose
Frequency
Ranitidine
Zantac
75 mg
75 mg BID
Famotidine
10 mg
BID
150 mg
150 mg BID
20 mg
BID
300 mg
Daily
40 mg
Daily
Cimetidine
Tagamet
300 mg
Q4-6hours
20 mg
BID
400 mg
BID
20 mg
BID
600-800 mg
Daily
40 mg
Daily
Nizatidine
Axid
75 mg
BID
10 mg
BID
150 mg
BID
20 mg
BID
300 mg
Daily
40 mg
Daily
Note: If the dosing falls outside of the above dosing, contact the MD to clarify conversion.
* Famotidine dosage will be adjusted to 20 mg q24h when CrCl < 50 ml/min and no active GI bleeding
** IV Cimetidine will be available for acute allergic reactions if desired
Ranitidine