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pegfilgrastim
pegfilgrastim
Brand names: Fulphila (pegfilgrastim-jmdb), Fylnetra, Neulasta, Neulasta Onpro Kit, Nyvepria (pegfilgrastim-apgf), Stimufend, Udenyca (pegfilgrastim-cbqv), Ziextenzo (pegfilgrastim-bmez)
| Form | Strength | ANAN | ASMP | LACH | LALK | LOHH | LOLR | LOWC | SDSD | SESE | SFSF | Formulary Status |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SOLUTION, SUBCUTANEOUS | 6 mg/0.6 mL; fpgk 6 mg/0.6 mL; pbbk 6 mg/0.6 mL | see comments |
Last updated: Nov. 27, 2024
- Therapeutic Interchange: Biosimilar and Reference Products Conversion List for Adults
- Do Not Tube-LALK
- Restricted: pegfilgrastim (Neulasta & Neulasta On-Body Injector) is restricted to use in the Outpatient setting
Medications Approved for Automatic Therapeutic Interchange Dosage Conversion Guidelines
(Note: “Therapeutic Interchange” should be placed in the order comments)
Biosimilar and Reference Products Interchange List for Adults
Medication
Reference Drug or Biosimilar
Formulary Status
Automatic Therapeutic Interchange
Inpatient1
Outpatient
Fulphila (pegfilgrastim-jmdb)
Biosimilar
Formulary, inpatient use restricted to criteria2
(preferred)
Use Fulphila when criteria2 met or recommend Granix
Use Fulphila unless third party payer requires other pegfilgrastim product
Fylnetra (pegfilgrastim-pbbk)
Biosimilar
Formulary preferred for OP
Interchange to Fulphila
Interchange to Fulphila unless third party payer requires other pegfilgrastim product
Udenyca (pegfilgrastim-cbqv), Udenyca OnBody, Udenyca AI, Ziextenzo (pegfilgrastim-bmez) Nyvepria (pegfilgrastim-apgf) Stimufend (pegfilgrastim-fpgk)
Biosimilars
Formulary, restricted to OP
(not preferred)
Interchange to Fulphila
Interchange to Fulphila unless third party payer requires other pegfilgrastim product
Neulasta (pegfilgrastim)
Reference
Neulasta and Udenyca are the only pegfilgrastim products with approval for hematopoietic radiation injury syndrome. Pegfilgrastim On-body will remain restricted to outpatient use only.
2Inpatient Pegfilgrastim Criteria:
Inpatient pegfilgrastim reminders: Patients meeting criteria will receive the formulary inpatient pegfilgrastim product. The NFT process must be completed for other inpatient pegfilgrastim products. Filgrastim is the preferred WBC growth factor for inpatient use; only a small number of patients will meet criteria for inpatient pegfilgrastim use.